| SP | Vazquez, J.Vazquez, Javier >> | 27 | 2003 | R | 93 | 13 | 12 | 3.24 | .267 | .270 | 1.11 | 7.7 | 2.2 | 9.4 | 230 | 198 | 28 | 57 | 241 | 4 | 0 | 11 | 119 | 19 | C |
| SP | Soto, M.Soto, Mario † >> | 28 | 1984 | R | 90 | 18 | 7 | 3.53 | .271 | .280 | 1.13 | 6.9 | 3.3 | 7.0 | 237 | 181 | 26 | 87 | 185 | 13 | 0 | 3 | 126 | 17 | C |
| SP | Hernandez, O.Hernandez, Orlando >> | 33 | 1998 | R | 88 | 12 | 4 | 3.13 | .276 | .280 | 1.17 | 7.2 | 3.3 | 8.4 | 141 | 113 | 11 | 52 | 131 | 3 | 0 | 5 | 118 | 18 | C |
| SP | Cook, D.Cook, Dennis >> | 27 | 1989 | L | 64 | 7 | 8 | 3.72 | .284 | .290 | 1.22 | 8.2 | 2.8 | 5.0 | 121 | 110 | 18 | 38 | 67 | 2 | 0 | 4 | 93 | 15 | C |
| SP | Millwood, K.Millwood, Kevin >> | 31 | 2005 | R | 62 | 9 | 11 | 2.86 | .285 | .290 | 1.22 | 8.5 | 2.4 | 6.8 | 192 | 182 | 20 | 52 | 146 | 1 | 0 | 2 | 113 | 16 | C |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 3 | 1 | 1.01 | .173 | .180 | 0.66 | 3.9 | 2.0 | 16.8 | 62 | 27 | 3 | 14 | 116 | 0 | 42 | 5 | 23 | 29 | C |
| RP | Hendriks, L.Hendriks, Liam >> | 32 | 2021 | R | 94 | 8 | 3 | 2.54 | .189 | .200 | 0.73 | 5.7 | 0.9 | 14.3 | 71 | 45 | 11 | 7 | 113 | 0 | 38 | 6 | 23 | 26 | C |
| SU | Percival, T.Percival, Troy >> | 26 | 1995 | R | 94 | 3 | 2 | 1.95 | .214 | .220 | 0.85 | 4.5 | 3.2 | 11.4 | 74 | 37 | 6 | 26 | 94 | 0 | 3 | 2 | 24 | 21 | C |
| RP | Casilla, S.Casilla, Santiago >> | 30 | 2010 | R | 43 | 7 | 2 | 1.95 | .274 | .290 | 1.20 | 6.5 | 4.3 | 9.2 | 55 | 40 | 2 | 26 | 56 | 0 | 2 | 10 | 23 | 19 | C |
| RP | Cishek, S.Cishek, Steven >> | 27 | 2013 | R | 58 | 4 | 6 | 2.33 | .257 | .270 | 1.09 | 6.9 | 2.9 | 9.7 | 69 | 53 | 3 | 22 | 74 | 0 | 34 | 1 | 23 | 20 | C |
| RP | Dotel, O.Dotel, Octavio >> | 28 | 2001 | R | 46 | 7 | 5 | 2.66 | .279 | .290 | 1.20 | 6.8 | 4.0 | 12.4 | 105 | 79 | 5 | 47 | 145 | 0 | 2 | 4 | 33 | 23 | C |
| RP | Stoddard, T.Stoddard, Tim >> | 26 | 1979 | R | 56 | 3 | 1 | 1.71 | .255 | .270 | 1.09 | 6.8 | 2.9 | 7.3 | 58 | 44 | 3 | 19 | 47 | 0 | 3 | 3 | 38 | 17 | C |
| RP | Marshall, M.Marshall, Mike >> | 29 | 1972 | R | 60 | 14 | 8 | 1.78 | .265 | .270 | 1.11 | 6.4 | 3.6 | 7.4 | 116 | 82 | 3 | 47 | 95 | 0 | 18 | 8 | 34 | 17 | C |
| SP | Harang, A.Harang, Aaron >> | 36 | 2014 | R | 11 | 12 | 12 | 3.57 | .315 | .320 | 1.40 | 9.5 | 3.1 | 7.1 | 204 | 215 | 15 | 71 | 161 | 0 | 0 | 9 | 109 | 17 | C |
| RP | Howell, J.Howell, Jay >> | 29 | 1984 | R | 36 | 9 | 4 | 2.69 | .273 | .280 | 1.17 | 7.5 | 3.0 | 9.5 | 103 | 86 | 5 | 34 | 109 | 0 | 7 | 4 | 33 | 19 | C |
| RP | Franklin, R.Franklin, Ryan >> | 36 | 2009 | R | 30 | 4 | 3 | 1.92 | .274 | .290 | 1.20 | 7.2 | 3.5 | 6.5 | 61 | 49 | 2 | 24 | 44 | 0 | 38 | 1 | 23 | 17 | C |
| RP | Assenmacher, P.Assenmacher, Paul >> | 26 | 1986 | L | 10 | 7 | 3 | 2.50 | .289 | .300 | 1.28 | 8.1 | 3.4 | 7.4 | 68 | 61 | 5 | 26 | 56 | 0 | 7 | 2 | 23 | 18 | C |
| SP | Caldwell, M.Caldwell, Mike >> | 25 | 1974 | L | 47 | 14 | 5 | 2.95 | .293 | .300 | 1.26 | 8.4 | 3.0 | 4.0 | 189 | 176 | 17 | 63 | 83 | 6 | 0 | 2 | 108 | 13 | C |
| SP | Andujar, J.Andujar, Joaquin >> | 33 | 1985 | R | 32 | 21 | 12 | 3.40 | .298 | .300 | 1.29 | 8.9 | 2.7 | 3.7 | 269 | 265 | 15 | 82 | 112 | 10 | 0 | 2 | 124 | 13 | C |
| RP | League, B.League, Brandon >> | 25 | 2008 | R | 11 | 1 | 2 | 2.18 | .283 | .310 | 1.30 | 7.6 | 4.1 | 6.3 | 33 | 28 | 2 | 15 | 23 | 0 | 1 | 2 | 23 | 17 | C |
| RP | Wickman, B.Wickman, Bob >> | 28 | 1997 | R | 2 | 7 | 6 | 2.73 | .306 | .320 | 1.37 | 8.4 | 3.9 | 7.4 | 95 | 89 | 8 | 41 | 78 | 0 | 1 | 8 | 26 | 17 | C |
| RP | Hanrahan, J.Hanrahan, Joel >> | 31 | 2012 | R | 37 | 5 | 2 | 2.72 | .289 | .300 | 1.29 | 6.1 | 5.5 | 10.2 | 59 | 40 | 8 | 36 | 67 | 0 | 36 | 6 | 23 | 21 | C |
| RP | Hawkins, L.Hawkins, LaTroy >> | 28 | 2000 | R | 1 | 2 | 5 | 3.39 | .302 | .310 | 1.34 | 8.8 | 3.3 | 6.1 | 87 | 85 | 7 | 32 | 59 | 0 | 14 | 6 | 26 | 16 | C |
| SP | Reuschel, R.Reuschel, Rick >> | 24 | 1973 | R | 30 | 14 | 15 | 3.00 | .298 | .300 | 1.29 | 9.3 | 2.4 | 6.4 | 237 | 244 | 15 | 62 | 168 | 7 | 0 | 10 | 116 | 16 | C |
| RP | Gott, J.Gott, Jim >> | 33 | 1992 | R | 19 | 3 | 3 | 2.45 | .292 | .300 | 1.28 | 7.4 | 4.2 | 7.7 | 88 | 72 | 4 | 41 | 75 | 0 | 6 | 9 | 26 | 18 | C |
| RP | Williams, M.Williams, Mitch >> | 25 | 1989 | L | 5 | 4 | 4 | 2.76 | .327 | .340 | 1.52 | 7.9 | 5.8 | 7.4 | 81 | 71 | 6 | 52 | 67 | 0 | 36 | 6 | 23 | 17 | C |
| RP | Garber, G.Garber, Gene >> | 39 | 1986 | R | 11 | 5 | 5 | 2.54 | .282 | .290 | 1.23 | 8.8 | 2.3 | 6.5 | 78 | 76 | 3 | 20 | 56 | 0 | 24 | 4 | 26 | 17 | C |
| SP | Marquez, G.Marquez, German >> | 22 | 2017 | R | 15 | 11 | 7 | 4.39 | .310 | .320 | 1.38 | 9.7 | 2.7 | 8.2 | 162 | 174 | 25 | 49 | 147 | 0 | 0 | 6 | 99 | 18 | C |
| SP | Zambrano, C.Zambrano, Carlos >> | 22 | 2003 | R | 44 | 13 | 11 | 3.11 | .302 | .310 | 1.32 | 7.9 | 4.0 | 7.1 | 214 | 188 | 9 | 94 | 168 | 3 | 0 | 6 | 118 | 17 | C |
| RP | Gordon, T.Gordon, Tom >> | 26 | 1993 | R | 20 | 12 | 6 | 3.58 | .298 | .310 | 1.30 | 7.3 | 4.5 | 8.3 | 155 | 125 | 11 | 77 | 143 | 2 | 1 | 17 | 59 | 18 | C |