| SP | Bumgarner, M.Bumgarner, Madison >> | 26 | 2016 | L | 98 | 15 | 9 | 2.74 | .252 | .260 | 1.03 | 7.1 | 2.2 | 10.0 | 226 | 178 | 26 | 54 | 251 | 4 | 0 | 4 | 117 | 20 | C |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 100 | 15 | 6 | 2.14 | .231 | .240 | 0.92 | 6.5 | 1.8 | 9.5 | 236 | 170 | 16 | 46 | 248 | 0 | 0 | 18 | 122 | 19 | C |
| SP | Garcia, F.Garcia, Freddy >> | 25 | 2001 | R | 87 | 18 | 6 | 3.05 | .270 | .280 | 1.13 | 7.5 | 2.6 | 6.2 | 238 | 199 | 16 | 69 | 163 | 4 | 0 | 3 | 123 | 16 | C |
| SP | Viola, F.Viola, Frank >> | 30 | 1990 | L | 77 | 20 | 12 | 2.67 | .275 | .280 | 1.15 | 8.2 | 2.2 | 6.6 | 249 | 227 | 15 | 60 | 182 | 7 | 0 | 11 | 125 | 16 | C |
| SP | Bannister, F.Bannister, Floyd >> | 28 | 1983 | L | 76 | 16 | 10 | 3.35 | .284 | .290 | 1.21 | 7.9 | 2.9 | 8.0 | 217 | 191 | 19 | 71 | 193 | 5 | 0 | 8 | 112 | 18 | C |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 100 | 3 | 2 | 1.83 | .177 | .190 | 0.68 | 4.6 | 1.5 | 13.8 | 68 | 35 | 4 | 11 | 104 | 0 | 47 | 1 | 23 | 24 | C |
| RP | Diaz, E.Diaz, Edwin >> | 24 | 2018 | R | 98 | 0 | 4 | 1.96 | .202 | .210 | 0.79 | 5.1 | 2.1 | 15.3 | 73 | 41 | 5 | 17 | 124 | 0 | 57 | 3 | 23 | 25 | C |
| RP | Hader, J.Hader, Josh >> | 25 | 2019 | L | 97 | 3 | 5 | 2.62 | .206 | .220 | 0.81 | 4.9 | 2.4 | 16.6 | 75 | 41 | 15 | 20 | 138 | 0 | 37 | 0 | 25 | 27 | C |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 88 | 2 | 4 | 1.60 | .218 | .230 | 0.87 | 5.9 | 2.0 | 11.7 | 78 | 51 | 6 | 17 | 101 | 0 | 46 | 2 | 24 | 22 | C |
| SU | Gossage, R.Gossage, Rich >> | 26 | 1977 | R | 87 | 11 | 9 | 1.62 | .237 | .250 | 0.95 | 5.3 | 3.3 | 10.2 | 133 | 78 | 9 | 49 | 151 | 0 | 26 | 2 | 35 | 20 | C |
| RP | Street, H.Street, Huston >> | 31 | 2014 | R | 77 | 2 | 2 | 1.37 | .230 | .240 | 0.95 | 6.4 | 2.1 | 8.7 | 59 | 42 | 4 | 14 | 57 | 0 | 41 | 0 | 23 | 19 | C |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 72 | 0 | 3 | 1.85 | .233 | .250 | 0.96 | 6.4 | 2.3 | 4.8 | 68 | 48 | 3 | 17 | 36 | 0 | 30 | 2 | 23 | 15 | C |
| RP | Doolittle, S.Doolittle, Sean >> | 26 | 2013 | L | 69 | 5 | 5 | 3.13 | .233 | .250 | 0.96 | 6.9 | 1.7 | 7.8 | 69 | 53 | 4 | 13 | 60 | 0 | 2 | 2 | 23 | 18 | C |
| RP | Hiller, J.Hiller, John >> | 33 | 1976 | L | 22 | 12 | 8 | 2.38 | .300 | .310 | 1.32 | 6.9 | 5.0 | 8.7 | 121 | 93 | 7 | 67 | 117 | 1 | 13 | 6 | 41 | 19 | C |
| RP | Abernathy, T.Abernathy, Ted >> | 32 | 1965 | R | 22 | 4 | 6 | 2.57 | .288 | .300 | 1.24 | 7.5 | 3.7 | 6.9 | 136 | 113 | 7 | 56 | 104 | 0 | 31 | 6 | 32 | 16 | C |
| SP | Whitson, E.Whitson, Ed >> | 25 | 1980 | R | 16 | 11 | 13 | 3.10 | .302 | .310 | 1.32 | 9.5 | 2.4 | 3.8 | 211 | 222 | 7 | 56 | 90 | 6 | 0 | 1 | 110 | 13 | C |
| SP | Matz, S.Matz, Steven >> | 32 | 2023 | L | 22 | 4 | 7 | 3.86 | .301 | .310 | 1.33 | 9.3 | 2.7 | 8.4 | 105 | 108 | 11 | 32 | 98 | 0 | 0 | 2 | 75 | 18 | C |
| RP | Storen, D.Storen, Drew >> | 23 | 2011 | R | 65 | 6 | 3 | 2.75 | .247 | .260 | 1.03 | 6.8 | 2.4 | 8.9 | 75 | 57 | 8 | 20 | 74 | 0 | 43 | 2 | 23 | 19 | C |
| RP | Julio, J.Julio, Jorge >> | 25 | 2004 | R | 10 | 2 | 5 | 4.57 | .311 | .320 | 1.42 | 7.7 | 5.1 | 9.1 | 69 | 59 | 11 | 39 | 70 | 0 | 22 | 7 | 23 | 20 | C |
| RP | Timlin, M.Timlin, Mike >> | 32 | 1998 | R | 18 | 3 | 3 | 2.95 | .276 | .290 | 1.19 | 8.9 | 1.8 | 6.8 | 79 | 78 | 5 | 16 | 60 | 0 | 19 | 0 | 23 | 17 | C |
| SP | Redman, M.Redman, Mark >> | 28 | 2002 | L | 24 | 8 | 15 | 4.21 | .297 | .300 | 1.29 | 9.4 | 2.3 | 4.8 | 203 | 211 | 15 | 51 | 109 | 3 | 0 | 11 | 119 | 14 | C |
| RP | Balfour, G.Balfour, Grant >> | 35 | 2012 | R | 88 | 3 | 2 | 2.53 | .229 | .240 | 0.93 | 5.0 | 3.4 | 8.8 | 74 | 41 | 4 | 28 | 72 | 0 | 24 | 2 | 23 | 19 | C |
| RP | Pena, A.Pena, Alejandro >> | 24 | 1983 | R | 33 | 12 | 9 | 2.75 | .273 | .280 | 1.15 | 7.7 | 2.6 | 6.1 | 177 | 152 | 7 | 51 | 120 | 4 | 1 | 2 | 92 | 16 | C |
| RP | Arroyo, L.Arroyo, Luis >> | 33 | 1960 | L | 23 | 5 | 1 | 2.88 | .286 | .310 | 1.30 | 6.8 | 5.0 | 6.5 | 40 | 30 | 2 | 22 | 29 | 0 | 7 | 0 | 27 | 17 | C |
| RP | Aase, D.Aase, Don >> | 23 | 1977 | R | 29 | 6 | 2 | 3.12 | .267 | .280 | 1.13 | 8.3 | 1.9 | 4.8 | 92 | 85 | 6 | 19 | 49 | 4 | 0 | 0 | 124 | 14 | C |
| RP | Madson, R.Madson, Ryan >> | 31 | 2011 | R | 30 | 4 | 2 | 2.37 | .269 | .280 | 1.17 | 8.1 | 2.4 | 9.3 | 60 | 54 | 2 | 16 | 62 | 0 | 32 | 0 | 23 | 20 | C |
| SP | Hurst, B.Hurst, Bruce >> | 28 | 1986 | L | 52 | 13 | 8 | 2.99 | .292 | .300 | 1.26 | 8.7 | 2.6 | 8.6 | 174 | 169 | 18 | 50 | 167 | 11 | 0 | 6 | 122 | 18 | C |
| SP | Cox, D.Cox, Danny >> | 28 | 1987 | R | 3 | 11 | 9 | 3.88 | .327 | .330 | 1.48 | 10.1 | 3.2 | 4.6 | 199 | 224 | 17 | 71 | 101 | 2 | 0 | 5 | 113 | 14 | C |
| RP | Rosenthal, T.Rosenthal, Trevor >> | 23 | 2013 | R | 52 | 2 | 4 | 2.63 | .261 | .270 | 1.11 | 7.6 | 2.4 | 13.0 | 75 | 63 | 4 | 20 | 108 | 0 | 3 | 3 | 23 | 23 | C |
| SP | Black, B.Black, Bud >> | 26 | 1983 | L | 40 | 10 | 7 | 3.79 | .291 | .300 | 1.25 | 8.9 | 2.4 | 3.2 | 161 | 159 | 19 | 43 | 58 | 3 | 0 | 4 | 118 | 13 | C |