| RP | Whitley, K.Whitley, Kodi >> | 26 | 2021 | R | 91 | 0 | 0 | 2.49 | .241 | .290 | 1.08 | 5.4 | 4.3 | 9.7 | 25 | 15 | 1 | 12 | 27 | 0 | 0 | 1 | 23 | 23 | C |
| RP | Cabrera, G.Cabrera, Genesis >> | 24 | 2021 | L | 72 | 4 | 5 | 3.73 | .286 | .320 | 1.26 | 6.7 | 4.6 | 9.9 | 70 | 52 | 3 | 36 | 77 | 0 | 0 | 9 | 23 | 21 | C |
| RP | Poncedeleon, D.Poncedeleon, Daniel >> | 29 | 2021 | R | 18 | 1 | 1 | 6.21 | .331 | .380 | 1.64 | 8.7 | 6.0 | 6.5 | 33 | 32 | 5 | 22 | 24 | 0 | 2 | 2 | 27 | 18 | C |
| RP | Gallegos, G.Gallegos, Giovanny >> | 29 | 2021 | R | 98 | 6 | 5 | 3.02 | .221 | .260 | 0.89 | 5.7 | 2.3 | 10.7 | 80 | 51 | 6 | 20 | 95 | 0 | 14 | 4 | 23 | 21 | C |
| RP | Webb, T.Webb, Tyler >> | 30 | 2021 | L | 2 | 0 | 0 | 13.22 | .414 | .490 | 2.56 | 12.4 | 10.7 | 7.9 | 16 | 22 | 1 | 19 | 14 | 0 | 0 | 1 | 23 | 24 | C |
| SP | Flaherty, J.Flaherty, Jack >> | 25 | 2021 | R | 93 | 9 | 2 | 3.22 | .254 | .290 | 1.06 | 6.6 | 3.0 | 9.8 | 78 | 57 | 12 | 26 | 85 | 0 | 0 | 4 | 82 | 20 | C |
| RP | Miller, A.Miller, Andrew >> | 36 | 2021 | L | 22 | 0 | 0 | 4.75 | .326 | .370 | 1.58 | 10.3 | 4.0 | 10.0 | 36 | 41 | 5 | 16 | 40 | 0 | 0 | 1 | 23 | 20 | C |
| RP | Helsley, R.Helsley, Ryan >> | 26 | 2021 | R | 48 | 6 | 4 | 4.56 | .307 | .350 | 1.43 | 7.7 | 5.2 | 9.0 | 47 | 40 | 4 | 27 | 47 | 0 | 1 | 7 | 23 | 19 | C |
| RP | Reyes, A.Reyes, Alex >> | 26 | 2021 | R | 72 | 10 | 8 | 3.24 | .302 | .340 | 1.36 | 5.8 | 6.5 | 11.9 | 72 | 46 | 9 | 52 | 95 | 0 | 29 | 10 | 23 | 21 | C |
| SP | Happ, J.Happ, J.A. >> | 39 | 2021 | L | 18 | 10 | 8 | 5.79 | .326 | .360 | 1.48 | 10.5 | 2.8 | 7.2 | 152 | 177 | 30 | 48 | 122 | 0 | 0 | 4 | 90 | 17 | C |
| RP | Garcia, L.Garcia, Luis >> | 34 | 2021 | R | 87 | 1 | 1 | 3.24 | .232 | .280 | 1.00 | 6.8 | 2.2 | 9.3 | 33 | 25 | 2 | 8 | 34 | 0 | 2 | 3 | 23 | 21 | C |
| SP | Mikolas, M.Mikolas, Miles >> | 32 | 2021 | R | 52 | 2 | 3 | 4.23 | .276 | .320 | 1.23 | 8.8 | 2.3 | 6.3 | 44 | 43 | 6 | 11 | 31 | 0 | 0 | 1 | 87 | 17 | C |
| SP | Wainwright, A.Wainwright, Adam >> | 40 | 2021 | R | 84 | 17 | 7 | 3.05 | .258 | .290 | 1.06 | 7.3 | 2.2 | 7.6 | 206 | 168 | 21 | 50 | 174 | 3 | 0 | 4 | 113 | 17 | C |
| SP | Oviedo, J.Oviedo, Johan >> | 23 | 2021 | R | 25 | 0 | 5 | 4.91 | .333 | .370 | 1.58 | 8.9 | 5.4 | 7.4 | 62 | 61 | 8 | 37 | 51 | 0 | 0 | 2 | 79 | 18 | C |
| SP | Martinez, C.Martinez, Carlos >> | 30 | 2021 | R | 34 | 4 | 9 | 6.23 | .306 | .340 | 1.38 | 8.5 | 4.0 | 6.3 | 82 | 77 | 8 | 36 | 57 | 0 | 0 | 3 | 91 | 16 | C |
| RP | McFarland, T.McFarland, T.J. >> | 32 | 2021 | L | 72 | 4 | 1 | 2.56 | .248 | .290 | 1.08 | 7.6 | 2.1 | 5.0 | 38 | 32 | 3 | 9 | 21 | 0 | 0 | 0 | 23 | 15 | C |
| RP | Gant, J.Gant, John >> | 28 | 2021 | R | 36 | 5 | 11 | 4.09 | .328 | .360 | 1.51 | 7.8 | 5.8 | 7.5 | 110 | 95 | 10 | 71 | 92 | 0 | 0 | 3 | 52 | 17 | C |
| RP | Woodford, J.Woodford, Jake >> | 24 | 2021 | R | 40 | 3 | 4 | 3.99 | .301 | .340 | 1.36 | 8.9 | 3.4 | 6.7 | 67 | 66 | 7 | 25 | 50 | 0 | 0 | 2 | 48 | 17 | C |
| SP | Hyun Kim, K.Hyun Kim, Kwang >> | 32 | 2021 | L | 46 | 7 | 7 | 3.46 | .295 | .330 | 1.29 | 8.3 | 3.3 | 6.8 | 106 | 98 | 12 | 39 | 80 | 0 | 1 | 4 | 71 | 17 | C |
| SP | Lester, J.Lester, Jon >> | 37 | 2021 | L | 15 | 7 | 6 | 4.71 | .331 | .360 | 1.52 | 10.1 | 3.5 | 5.8 | 141 | 159 | 25 | 55 | 91 | 0 | 0 | 0 | 90 | 16 | C |
| RP | LeBlanc, W.LeBlanc, Wade >> | 37 | 2021 | L | 21 | 0 | 2 | 4.41 | .317 | .360 | 1.49 | 10.3 | 3.1 | 5.3 | 49 | 56 | 8 | 17 | 29 | 0 | 0 | 2 | 50 | 15 | C |
| RP | Fernandez, J.Fernandez, Junior >> | 24 | 2021 | R | 4 | 1 | 0 | 5.66 | .364 | .430 | 2.00 | 11.3 | 6.8 | 6.8 | 20 | 25 | 2 | 15 | 15 | 0 | 0 | 1 | 23 | 17 | C |
| RP | Miller, J.Miller, Justin >> | 34 | 2021 | R | 50 | 1 | 0 | 4.50 | .256 | .320 | 1.25 | 8.4 | 2.8 | 5.1 | 16 | 15 | 2 | 5 | 9 | 0 | 1 | 0 | 23 | 19 | C |