| SP | Sandoval, P.Sandoval, Patrick >> | 24 | 2021 | L | 80 | 3 | 6 | 3.62 | .279 | .310 | 1.21 | 7.1 | 3.7 | 9.7 | 87 | 69 | 11 | 36 | 94 | 0 | 1 | 3 | 91 | 20 | C |
| RP | Quintana, J.Quintana, Jose >> | 32 | 2021 | L | 18 | 0 | 3 | 6.43 | .354 | .390 | 1.73 | 10.6 | 5.0 | 12.1 | 63 | 74 | 12 | 35 | 85 | 0 | 0 | 7 | 41 | 22 | C |
| SP | Barria, J.Barria, Jaime >> | 24 | 2021 | R | 9 | 2 | 4 | 4.61 | .333 | .370 | 1.59 | 11.3 | 3.1 | 5.6 | 56 | 70 | 8 | 19 | 35 | 0 | 0 | 0 | 77 | 15 | C |
| SP | Junk, J.Junk, Janson >> | 25 | 2021 | R | 22 | 0 | 1 | 3.86 | .275 | .340 | 1.38 | 11.3 | 1.1 | 5.6 | 16 | 20 | 5 | 2 | 10 | 0 | 0 | 0 | 72 | 20 | C |
| RP | Mayers, M.Mayers, Mike >> | 29 | 2021 | R | 54 | 5 | 5 | 3.84 | .292 | .330 | 1.29 | 8.5 | 3.1 | 10.8 | 75 | 71 | 11 | 26 | 90 | 0 | 2 | 0 | 23 | 21 | C |
| SP | Bundy, D.Bundy, Dylan >> | 29 | 2021 | R | 37 | 2 | 9 | 6.06 | .305 | .340 | 1.37 | 8.9 | 3.4 | 8.4 | 90 | 89 | 20 | 34 | 84 | 0 | 0 | 1 | 71 | 18 | C |
| RP | Naughton, P.Naughton, Packy >> | 25 | 2021 | L | 4 | 0 | 4 | 6.35 | .350 | .410 | 1.86 | 11.0 | 5.7 | 4.9 | 22 | 27 | 3 | 14 | 12 | 0 | 0 | 0 | 57 | 16 | C |
| RP | Iglesias, R.Iglesias, Raisel >> | 31 | 2021 | R | 95 | 7 | 5 | 2.57 | .228 | .260 | 0.93 | 6.8 | 1.5 | 13.2 | 70 | 53 | 11 | 12 | 103 | 0 | 34 | 2 | 23 | 24 | C |
| RP | Warren, A.Warren, Austin >> | 25 | 2021 | R | 80 | 3 | 0 | 1.77 | .231 | .290 | 1.05 | 7.2 | 2.3 | 9.0 | 20 | 16 | 0 | 5 | 20 | 0 | 1 | 0 | 25 | 20 | C |
| RP | Watson, T.Watson, Tony >> | 36 | 2021 | L | 86 | 7 | 4 | 3.92 | .243 | .280 | 1.02 | 6.3 | 2.8 | 6.9 | 57 | 40 | 4 | 18 | 44 | 0 | 0 | 0 | 23 | 17 | C |
| RP | Quijada, J.Quijada, Jose >> | 25 | 2021 | L | 60 | 0 | 2 | 4.56 | .292 | .350 | 1.40 | 7.2 | 5.4 | 13.7 | 25 | 20 | 2 | 15 | 38 | 0 | 0 | 1 | 23 | 29 | C |
| RP | Guerra, J.Guerra, Junior >> | 36 | 2021 | R | 15 | 5 | 2 | 6.06 | .355 | .390 | 1.74 | 9.3 | 6.4 | 8.4 | 65 | 67 | 6 | 46 | 61 | 0 | 0 | 9 | 31 | 18 | C |
| SP | Canning, G.Canning, Griffin >> | 25 | 2021 | R | 27 | 5 | 4 | 5.60 | .322 | .360 | 1.50 | 9.4 | 4.1 | 9.0 | 62 | 65 | 14 | 28 | 62 | 0 | 0 | 3 | 79 | 20 | C |
| RP | Slegers, A.Slegers, Aaron >> | 28 | 2021 | R | 3 | 2 | 2 | 6.97 | .360 | .410 | 1.87 | 12.5 | 4.4 | 7.3 | 31 | 43 | 6 | 15 | 25 | 0 | 0 | 1 | 23 | 18 | C |
| RP | Wantz, A.Wantz, Andrew >> | 25 | 2021 | R | 68 | 1 | 0 | 4.94 | .272 | .320 | 1.26 | 7.7 | 3.7 | 12.7 | 27 | 23 | 5 | 11 | 38 | 0 | 0 | 1 | 26 | 22 | C |
| SP | Ohtani, S.Ohtani, Shohei >> | 26 | 2021 | R | 92 | 9 | 2 | 3.18 | .262 | .290 | 1.09 | 6.8 | 3.0 | 10.8 | 130 | 98 | 15 | 44 | 156 | 0 | 0 | 10 | 100 | 21 | C |
| RP | Rodriguez, C.Rodriguez, Chris >> | 22 | 2021 | R | 34 | 2 | 1 | 3.64 | .307 | .360 | 1.48 | 8.7 | 4.7 | 9.0 | 29 | 28 | 0 | 15 | 29 | 0 | 0 | 1 | 37 | 19 | C |
| SP | Cobb, A.Cobb, Alex >> | 33 | 2021 | R | 60 | 8 | 3 | 3.76 | .290 | .330 | 1.27 | 8.2 | 3.2 | 9.5 | 93 | 85 | 5 | 33 | 98 | 0 | 0 | 4 | 92 | 19 | C |
| RP | Cishek, S.Cishek, Steven >> | 35 | 2021 | R | 35 | 0 | 2 | 3.42 | .323 | .360 | 1.50 | 8.1 | 5.4 | 8.5 | 68 | 61 | 2 | 41 | 64 | 0 | 0 | 4 | 23 | 19 | C |
| SP | Detmers, R.Detmers, Reid >> | 21 | 2021 | L | 6 | 1 | 3 | 7.40 | .346 | .410 | 1.85 | 11.7 | 5.0 | 8.6 | 20 | 26 | 5 | 11 | 19 | 0 | 0 | 1 | 72 | 19 | C |
| RP | Strickland, H.Strickland, Hunter >> | 32 | 2021 | R | 74 | 3 | 2 | 2.61 | .270 | .310 | 1.17 | 7.1 | 3.4 | 9.0 | 58 | 46 | 8 | 22 | 58 | 0 | 0 | 3 | 23 | 19 | C |
| RP | Claudio, A.Claudio, Alex >> | 29 | 2021 | L | 13 | 1 | 2 | 5.51 | .329 | .380 | 1.63 | 10.4 | 4.2 | 8.4 | 32 | 37 | 6 | 15 | 30 | 0 | 1 | 1 | 23 | 20 | C |
| RP | Selman, S.Selman, Sam >> | 30 | 2021 | L | 59 | 0 | 1 | 5.76 | .274 | .330 | 1.28 | 7.2 | 4.3 | 6.8 | 25 | 20 | 3 | 12 | 19 | 0 | 0 | 0 | 23 | 19 | C |
| SP | Heaney, A.Heaney, Andrew >> | 30 | 2021 | L | 44 | 8 | 9 | 5.83 | .301 | .330 | 1.33 | 9.1 | 2.9 | 10.5 | 129 | 130 | 29 | 41 | 150 | 0 | 0 | 4 | 77 | 20 | C |
| SP | Suarez, J.Suarez, Jose >> | 23 | 2021 | L | 64 | 8 | 8 | 3.75 | .285 | .320 | 1.23 | 7.8 | 3.3 | 7.8 | 98 | 85 | 11 | 36 | 85 | 1 | 0 | 4 | 76 | 18 | C |