| C(1B) | Stubbs, G.Stubbs, Garrett >> | 29 | 2022 | L | 88 | 86 | 59 | 46 | .264 | .350 | .462 | .812 | .330 | 106 | 19 | 28 | 4 | 1 | 5 | 16 | 14 | 30 | 0 | 2 | .990 | - | +0.2 | 5 | +1.1 | 4 | C |
| 1B(OF) | Ramirez, H.Ramirez, Harold >> | 27 | 2022 | R | 77 | 88 | 8 | 120 | .300 | .346 | .404 | .750 | .330 | 403 | 46 | 121 | 24 | 0 | 6 | 58 | 19 | 72 | 9 | 3 | .984 | - | -1.3 | 2 | +1.7 | 6 | C |
| 2B(IF) | Altuve, J.Altuve, Jose >> | 32 | 2022 | R | 89 | 99 | 6 | 141 | .300 | .388 | .533 | .921 | .370 | 527 | 103 | 158 | 39 | 0 | 28 | 57 | 66 | 87 | 10 | 18 | .979 | - | -1.2 | 5 | +6.8 | 10 | C |
| 2B(1B) | Cronenworth, J.Cronenworth, Jake >> | 28 | 2022 | L | 76 | 66 | 72 | 158 | .240 | .337 | .394 | .731 | .320 | 587 | 88 | 141 | 31 | 4 | 17 | 88 | 70 | 131 | 16 | 3 | .992 | - | +0.3 | 3 | +4.3 | 42 | C |
| 3B(IF) | Arenado, N.Arenado, Nolan † >> | 31 | 2022 | R | 98 | 96 | 78 | 148 | .293 | .360 | .533 | .893 | .340 | 557 | 73 | 163 | 42 | 1 | 30 | 103 | 52 | 72 | 7 | 5 | .968 | - | +2.3 | 2 | +5.8 | 14 | C |
| 3B(IF) | Chapman, M.Chapman, Matt >> | 29 | 2022 | R | 71 | 62 | 78 | 155 | .229 | .326 | .433 | .759 | .310 | 538 | 83 | 123 | 27 | 1 | 27 | 76 | 68 | 170 | 10 | 2 | .988 | - | +0.6 | 2 | +3.4 | 25 | C |
| SS(IF) | Correa, C.Correa, Carlos † >> | 27 | 2022 | R | 99 | 95 | 81 | 136 | .291 | .369 | .467 | .836 | .350 | 522 | 70 | 152 | 24 | 1 | 22 | 64 | 61 | 121 | 3 | 0 | .983 | - | +1.1 | 2 | +5.2 | 8 | C |
| OF(OF) | Hernandez, T.Hernandez, Teoscar >> | 29 | 2022 | R | 63 | 76 | 17 | 131 | .267 | .316 | .491 | .807 | .300 | 499 | 71 | 133 | 35 | 1 | 25 | 77 | 34 | 152 | 2 | 6 | .984 | - | -0.8 | 3 | +3 | 7 | C |
| OF(1B) | Carpenter, M.Carpenter, Matt † >> | 36 | 2022 | L | 99 | 100 | 55 | 47 | .305 | .414 | .727 | 1.141 | .400 | 128 | 28 | 39 | 9 | 0 | 15 | 37 | 19 | 35 | 5 | 0 | 1.000 | - | -0.3 | 1 | +2.4 | 4 | C |
| OF(OF) | Pederson, J.Pederson, Joc >> | 30 | 2022 | L | 82 | 93 | 5 | 134 | .274 | .357 | .521 | .878 | .340 | 380 | 57 | 104 | 19 | 3 | 23 | 70 | 42 | 100 | 7 | 3 | .986 | - | -2.1 | 4 | +2.8 | 8 | C |
| OF(OF) | Meadows, A.Meadows, Austin >> | 27 | 2022 | L | 80 | 64 | 87 | 36 | .250 | .347 | .328 | .675 | .330 | 128 | 9 | 32 | 6 | 2 | 0 | 11 | 16 | 17 | 3 | 0 | 1.000 | - | +0.3 | 4 | +0.3 | 4 | C |