| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 67 | 10 | 10 | 4 | 4 | 3.44 | .274 | 1.13 | 8.6 | 1.6 | 5.3 | 68.0 | 65 | 31 | 26 | 7 | 12 | 40 | 2 | 0 | 0 | 1 | 6 | 0 | 2 | 3.69 |
| SP | Wheeler, Z.Wheeler, Zack >> | 35 | 2025 | R | 84 | 9 | 9 | 3 | 3 | 6.36 | .338 | 1.51 | 10.7 | 2.9 | 8.7 | 52.1 | 62 | 44 | 37 | 15 | 17 | 50 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.87 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 55 | 10 | 9 | 5 | 2 | 4.85 | .321 | 1.40 | 9.8 | 2.9 | 7.3 | 59.1 | 64 | 38 | 32 | 11 | 19 | 48 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 4.81 |
| RP | Strahm, M.Strahm, Matt >> | 32 | 2024 | L | 93 | 26 | 0 | 0 | 1 | 4.15 | .386 | 1.88 | 11.4 | 5.5 | 9.7 | 26.0 | 33 | 16 | 12 | 4 | 16 | 28 | 0 | 5 | 0 | 0 | 0 | 0 | 2 | 4.69 |
| RP | Valdes, R.Valdes, Raul >> | 34 | 2012 | L | 92 | 20 | 0 | 2 | 0 | 6.75 | .345 | 1.58 | 12.0 | 2.3 | 7.9 | 24.0 | 32 | 23 | 18 | 5 | 6 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.71 |
| CL | Wagner, B.Wagner, Billy >> | 33 | 2004 | L | 83 | 18 | 0 | 2 | 2 | 5.12 | .293 | 1.19 | 9.9 | 0.9 | 10.4 | 19.1 | 21 | 12 | 11 | 5 | 2 | 22 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 4.58 |
| RP | Bastardo, A.Bastardo, Antonio >> | 26 | 2011 | L | 75 | 21 | 0 | 2 | 1 | 2.05 | .282 | 1.14 | 5.5 | 4.8 | 9.0 | 26.1 | 16 | 9 | 6 | 2 | 14 | 26 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.73 |
| RP | Hoffman, J.Hoffman, Jeff >> | 30 | 2023 | R | 70 | 11 | 0 | 1 | 0 | 3.65 | .275 | 1.14 | 9.8 | 0.8 | 9.0 | 12.1 | 13 | 7 | 5 | 3 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |
| RP | Madson, R.Madson, Ryan >> | 30 | 2010 | R | 37 | 12 | 0 | 0 | 0 | 1.32 | .317 | 1.39 | 4.2 | 9.0 | 6.9 | 13.2 | 6 | 2 | 2 | 0 | 13 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.46 |