| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 55 | 8 | 8 | 1 | 2 | 7.71 | .402 | 1.99 | 10.6 | 7.6 | 6.2 | 39.2 | 46 | 34 | 34 | 3 | 33 | 27 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.23 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 60 | 25 | 0 | 2 | 1 | 5.40 | .357 | 1.66 | 9.0 | 6.3 | 9.5 | 36.2 | 36 | 23 | 22 | 3 | 25 | 38 | 0 | 1 | 0 | 0 | 0 | 0 | 7 | 4.06 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 40 | 9 | 9 | 4 | 2 | 5.08 | .370 | 1.74 | 10.4 | 5.3 | 8.8 | 44.1 | 51 | 28 | 25 | 5 | 26 | 43 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.36 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 61 | 23 | 0 | 6 | 2 | 4.34 | .317 | 1.37 | 10.5 | 1.9 | 8.5 | 37.1 | 43 | 20 | 18 | 4 | 8 | 35 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.24 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 54 | 22 | 0 | 2 | 1 | 1.34 | .273 | 1.10 | 6.0 | 4.1 | 10.6 | 33.2 | 22 | 5 | 5 | 2 | 15 | 39 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 2.88 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 59 | 17 | 0 | 0 | 3 | 3.71 | .279 | 1.16 | 5.5 | 5.2 | 8.3 | 26.2 | 16 | 11 | 11 | 2 | 15 | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.88 |
| RP | Buchholz, T.Buchholz, Taylor >> | 27 | 2008 | R | 45 | 21 | 0 | 2 | 0 | 6.15 | .307 | 1.29 | 8.0 | 3.8 | 8.7 | 26.1 | 23 | 19 | 18 | 5 | 11 | 25 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.96 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 30 | 2011 | L | 44 | 8 | 8 | 0 | 1 | 7.59 | .373 | 1.73 | 11.1 | 4.7 | 7.7 | 21.1 | 26 | 18 | 18 | 5 | 11 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 6.10 |
| SP | Gilbreath, L.Gilbreath, Lucas >> | 25 | 2021 | L | 34 | 8 | 8 | 0 | 2 | 7.80 | .444 | 2.33 | 10.2 | 10.8 | 6.6 | 15.0 | 17 | 14 | 13 | 2 | 18 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 7.07 |