| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 87 | 10 | 10 | 4 | 4 | 3.69 | .280 | 1.11 | 6.9 | 3.1 | 7.9 | 63.1 | 48 | 26 | 26 | 1 | 22 | 55 | 2 | 0 | 0 | 0 | 6 | 4 | 0 | 2.70 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 96 | 10 | 10 | 5 | 2 | 3.39 | .307 | 1.33 | 10.0 | 2.0 | 8.3 | 66.1 | 73 | 25 | 25 | 4 | 15 | 61 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 2.62 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 74 | 10 | 10 | 4 | 3 | 4.27 | .309 | 1.32 | 8.7 | 3.2 | 5.0 | 59.0 | 57 | 29 | 28 | 8 | 21 | 33 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 4.76 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 24 | 2013 | R | 64 | 10 | 9 | 1 | 3 | 6.69 | .343 | 1.57 | 10.5 | 3.8 | 9.3 | 36.1 | 42 | 28 | 27 | 11 | 15 | 37 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 6.17 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 94 | 26 | 0 | 3 | 2 | 1.62 | .236 | 0.88 | 5.9 | 2.0 | 6.3 | 44.1 | 29 | 10 | 8 | 5 | 10 | 31 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 3.89 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 78 | 23 | 0 | 2 | 1 | 4.76 | .320 | 1.38 | 9.0 | 3.5 | 10.3 | 28.1 | 28 | 16 | 15 | 3 | 11 | 32 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.39 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 23 | 0 | 3 | 3 | 5.26 | .306 | 1.32 | 7.9 | 4.3 | 11.2 | 25.2 | 22 | 15 | 15 | 4 | 12 | 31 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 4.04 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 87 | 24 | 0 | 0 | 1 | 5.06 | .339 | 1.50 | 8.3 | 5.5 | 6.9 | 26.2 | 24 | 15 | 15 | 4 | 16 | 20 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 5.42 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 64 | 21 | 0 | 1 | 0 | 3.76 | .269 | 1.10 | 7.3 | 2.8 | 7.6 | 26.1 | 21 | 11 | 11 | 3 | 8 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.73 |
| RP | Hudson, D.Hudson, Daniel >> | 34 | 2021 | R | 54 | 20 | 0 | 0 | 2 | 6.00 | .330 | 1.48 | 11.6 | 1.7 | 8.6 | 21.0 | 27 | 15 | 14 | 5 | 4 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.76 |
| RP | Rivero, F.Rivero, Felipe >> | 23 | 2015 | L | 40 | 18 | 0 | 0 | 0 | 10.57 | .395 | 1.96 | 14.4 | 3.6 | 6.6 | 15.1 | 24 | 18 | 18 | 4 | 6 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 6.20 |