| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 13 | 13 | 6 | 7 | 2.95 | .249 | 0.97 | 7.1 | 1.7 | 4.2 | 97.2 | 77 | 39 | 32 | 8 | 18 | 45 | 4 | 0 | 0 | 0 | 11 | 2 | 1 | 3.76 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 13 | 13 | 5 | 7 | 3.84 | .303 | 1.28 | 9.8 | 1.7 | 5.6 | 98.1 | 107 | 47 | 42 | 6 | 19 | 61 | 4 | 0 | 0 | 1 | 7 | 2 | 0 | 3.19 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 13 | 13 | 6 | 5 | 3.87 | .287 | 1.19 | 8.2 | 2.5 | 8.0 | 86.0 | 78 | 40 | 37 | 12 | 24 | 76 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 3.95 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 22 | 0 | 1 | 0 | 1.54 | .186 | 0.69 | 3.9 | 2.3 | 5.5 | 23.1 | 10 | 4 | 4 | 2 | 6 | 14 | 0 | 17 | 0 | 0 | 0 | 0 | 2 | 3.70 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 17 | 0 | 0 | 1 | 4.50 | .262 | 1.06 | 9.0 | 0.6 | 6.8 | 16.0 | 16 | 8 | 8 | 0 | 1 | 12 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 1.69 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 24 | 0 | 1 | 0 | 4.15 | .322 | 1.42 | 8.7 | 4.2 | 9.3 | 26.0 | 25 | 12 | 12 | 3 | 12 | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.81 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 21 | 0 | 2 | 1 | 6.39 | .303 | 1.30 | 6.8 | 5.0 | 7.9 | 25.1 | 19 | 18 | 18 | 6 | 14 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.04 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 6 | 0 | 0 | 0 | 0.00 | .214 | 0.82 | 3.9 | 3.9 | 11.6 | 7.1 | 3 | 0 | 0 | 0 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.71 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 5 | 0 | 1 | 0 | 2.92 | .267 | 1.09 | 7.9 | 2.3 | 5.3 | 24.2 | 21 | 10 | 8 | 3 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.21 |