| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 13 | 13 | 4 | 8 | 2.66 | .248 | 0.99 | 6.2 | 2.7 | 5.0 | 88.0 | 61 | 26 | 26 | 9 | 26 | 49 | 3 | 0 | 0 | 1 | 10 | 0 | 0 | 4.10 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 13 | 13 | 5 | 7 | 4.17 | .307 | 1.33 | 7.2 | 4.8 | 5.6 | 77.2 | 62 | 40 | 36 | 8 | 41 | 48 | 1 | 0 | 0 | 0 | 8 | 0 | 3 | 4.70 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 13 | 13 | 7 | 1 | 4.00 | .293 | 1.24 | 9.2 | 2.1 | 8.8 | 87.2 | 89 | 40 | 39 | 10 | 20 | 85 | 3 | 0 | 0 | 0 | 8 | 0 | 0 | 3.23 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 13 | 13 | 4 | 4 | 4.80 | .276 | 1.12 | 8.2 | 1.9 | 5.8 | 90.0 | 82 | 50 | 48 | 14 | 19 | 58 | 3 | 0 | 0 | 1 | 5 | 2 | 1 | 4.43 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 32 | 0 | 3 | 0 | 2.85 | .241 | 0.93 | 6.3 | 2.1 | 8.6 | 47.1 | 33 | 17 | 15 | 5 | 11 | 45 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.23 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 27 | 0 | 2 | 0 | 6.08 | .360 | 1.69 | 11.1 | 4.5 | 11.1 | 26.2 | 32 | 19 | 18 | 6 | 13 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.04 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 18 | 0 | 1 | 1 | 3.86 | .267 | 1.10 | 7.7 | 2.1 | 7.3 | 21.0 | 18 | 9 | 9 | 4 | 5 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.57 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 24 | 0 | 3 | 4 | 3.18 | .280 | 1.13 | 8.4 | 1.9 | 7.7 | 28.1 | 26 | 10 | 10 | 3 | 6 | 24 | 0 | 9 | 0 | 0 | 0 | 1 | 0 | 3.43 |