| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 10 | 10 | 3 | 3 | 3.60 | .300 | 1.26 | 8.5 | 2.8 | 4.5 | 70.0 | 66 | 28 | 28 | 6 | 22 | 35 | 4 | 0 | 0 | 1 | 5 | 2 | 1 | 4.14 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 11 | 11 | 4 | 5 | 4.97 | .344 | 1.57 | 8.9 | 5.4 | 4.6 | 70.2 | 69 | 41 | 39 | 6 | 42 | 36 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 4.89 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 70 | 11 | 11 | 4 | 5 | 5.40 | .318 | 1.39 | 8.0 | 4.4 | 5.4 | 75.0 | 67 | 47 | 45 | 16 | 37 | 45 | 3 | 0 | 0 | 0 | 4 | 1 | 2 | 6.09 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 10 | 10 | 5 | 5 | 4.07 | .293 | 1.24 | 8.6 | 2.6 | 3.5 | 77.1 | 74 | 36 | 35 | 12 | 22 | 30 | 6 | 0 | 0 | 0 | 5 | 0 | 4 | 5.10 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 26 | 0 | 0 | 3 | 5.34 | .381 | 1.81 | 9.0 | 7.5 | 7.5 | 30.1 | 30 | 19 | 18 | 3 | 25 | 25 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 5.23 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 22 | 0 | 3 | 1 | 3.14 | .252 | 1.01 | 6.4 | 2.9 | 6.4 | 28.2 | 20 | 11 | 10 | 2 | 9 | 20 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.46 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 15 | 0 | 1 | 2 | 4.63 | .386 | 1.89 | 9.8 | 8.2 | 9.0 | 11.2 | 12 | 6 | 6 | 0 | 10 | 11 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.73 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 12 | 0 | 0 | 0 | 4.50 | .284 | 1.19 | 7.3 | 3.4 | 5.6 | 16.0 | 13 | 8 | 8 | 4 | 6 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.13 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 51 | 2 | 2 | 1 | 1 | 5.84 | .339 | 1.54 | 12.0 | 2.3 | 6.8 | 12.1 | 16 | 8 | 8 | 1 | 3 | 9 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.33 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 0 | 0 | 0 | 6.75 | .467 | 2.63 | 18.0 | 13.5 | 0.0 | 2.2 | 4 | 2 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.50 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 56 | 3 | 0 | 1 | 0 | 11.12 | .452 | 2.47 | 18.0 | 7.2 | 3.6 | 5.2 | 10 | 7 | 7 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.60 |