| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 14 | 14 | 4 | 6 | 3.50 | .302 | 1.29 | 8.4 | 3.2 | 8.0 | 100.1 | 93 | 44 | 39 | 12 | 36 | 89 | 2 | 0 | 0 | 0 | 9 | 1 | 0 | 3.89 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 13 | 13 | 8 | 3 | 3.40 | .247 | 0.98 | 7.0 | 1.9 | 7.6 | 100.2 | 78 | 38 | 38 | 13 | 21 | 84 | 5 | 0 | 0 | 0 | 8 | 0 | 1 | 3.64 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 13 | 4 | 7 | 6.37 | .362 | 1.66 | 11.1 | 4.0 | 5.3 | 77.2 | 95 | 58 | 55 | 13 | 34 | 45 | 0 | 0 | 0 | 0 | 6 | 3 | 0 | 5.47 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 30 | 0 | 1 | 2 | 3.78 | .310 | 1.35 | 9.3 | 3.0 | 8.5 | 33.1 | 34 | 14 | 14 | 4 | 11 | 31 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 3.70 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 27 | 0 | 2 | 1 | 4.91 | .305 | 1.29 | 7.9 | 3.8 | 5.9 | 40.1 | 35 | 24 | 22 | 5 | 17 | 26 | 0 | 4 | 1 | 0 | 0 | 1 | 4 | 4.68 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 5 | 0 | 0 | 2 | 12.27 | .476 | 2.73 | 19.3 | 6.4 | 7.7 | 7.1 | 15 | 10 | 10 | 3 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.00 |