| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 20 | 20 | 3 | 11 | 5.50 | .327 | 1.43 | 9.5 | 3.4 | 8.9 | 127.2 | 134 | 79 | 78 | 19 | 48 | 126 | 3 | 0 | 0 | 0 | 7 | 4 | 3 | 4.19 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 19 | 19 | 8 | 6 | 4.13 | .283 | 1.16 | 8.0 | 2.5 | 8.4 | 128.2 | 114 | 66 | 59 | 16 | 35 | 119 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 3.66 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 18 | 18 | 7 | 6 | 3.49 | .298 | 1.26 | 8.2 | 3.1 | 5.2 | 126.1 | 115 | 50 | 49 | 9 | 44 | 73 | 3 | 0 | 0 | 1 | 12 | 2 | 2 | 3.87 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 18 | 18 | 6 | 9 | 5.19 | .330 | 1.45 | 9.1 | 3.9 | 4.5 | 121.1 | 123 | 73 | 70 | 16 | 53 | 60 | 3 | 0 | 0 | 0 | 6 | 3 | 1 | 5.12 |
| SP | Krause, H.Krause, Harry † >> | 21 | 1909 | L | 72 | 18 | 18 | 14 | 2 | 4.14 | .312 | 1.33 | 9.0 | 3.0 | 4.6 | 115.1 | 115 | 56 | 53 | 10 | 38 | 59 | 1 | 0 | 0 | 0 | 9 | 4 | 0 | 4.20 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 33 | 0 | 1 | 2 | 2.38 | .221 | 0.85 | 3.7 | 4.0 | 9.8 | 34.0 | 14 | 10 | 9 | 2 | 15 | 37 | 0 | 28 | 2 | 0 | 0 | 0 | 1 | 2.91 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 30 | 0 | 1 | 0 | 2.45 | .290 | 1.20 | 7.0 | 4.0 | 7.5 | 36.2 | 28 | 12 | 10 | 4 | 16 | 30 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 4.19 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 28 | 0 | 2 | 2 | 5.04 | .336 | 1.44 | 8.3 | 4.7 | 10.8 | 25.0 | 23 | 15 | 14 | 1 | 13 | 30 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 2.92 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 17 | 0 | 0 | 1 | 2.18 | .205 | 0.73 | 6.3 | 0.5 | 10.8 | 20.2 | 14 | 5 | 5 | 3 | 1 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.85 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 13 | 0 | 2 | 0 | 4.76 | .404 | 2.03 | 13.1 | 5.7 | 9.0 | 11.1 | 16 | 9 | 6 | 3 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.45 |
| RP | Wohlers, M.Wohlers, Mark >> | 25 | 1995 | R | 10 | 14 | 0 | 0 | 0 | 3.12 | .316 | 1.38 | 8.5 | 4.2 | 6.4 | 17.1 | 16 | 8 | 6 | 7 | 8 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 8.35 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 5 | 0 | 1 | 0 | 2.66 | .317 | 1.35 | 9.0 | 3.5 | 3.5 | 23.2 | 23 | 10 | 7 | 1 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.09 |