| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 30 | 30 | 9 | 12 | 3.84 | .301 | 1.28 | 8.2 | 3.3 | 8.7 | 194.2 | 177 | 89 | 83 | 18 | 72 | 187 | 1 | 0 | 0 | 0 | 22 | 3 | 4 | 3.44 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 29 | 29 | 8 | 11 | 4.84 | .309 | 1.33 | 8.6 | 3.4 | 8.5 | 189.2 | 181 | 104 | 102 | 28 | 71 | 179 | 1 | 0 | 0 | 0 | 14 | 3 | 3 | 4.21 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 29 | 29 | 9 | 9 | 4.91 | .308 | 1.30 | 9.0 | 2.8 | 6.2 | 150.1 | 150 | 84 | 82 | 24 | 46 | 103 | 0 | 0 | 0 | 0 | 8 | 5 | 5 | 4.73 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 29 | 29 | 6 | 15 | 5.29 | .323 | 1.43 | 9.8 | 3.1 | 4.3 | 202.1 | 220 | 131 | 119 | 35 | 69 | 97 | 5 | 0 | 0 | 1 | 8 | 0 | 2 | 5.32 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 29 | 27 | 12 | 9 | 5.17 | .337 | 1.48 | 9.8 | 3.6 | 4.8 | 175.2 | 190 | 107 | 101 | 22 | 70 | 94 | 5 | 0 | 0 | 0 | 12 | 8 | 3 | 4.90 |
| SU | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 57 | 0 | 2 | 4 | 3.34 | .281 | 1.13 | 8.2 | 2.1 | 11.7 | 64.2 | 58 | 24 | 24 | 9 | 15 | 83 | 0 | 5 | 4 | 0 | 0 | 3 | 0 | 3.08 |
| CL | Gossage, R.Gossage, Rich † >> | 30 | 1981 | R | 90 | 63 | 0 | 1 | 8 | 2.74 | .259 | 1.01 | 6.3 | 2.9 | 7.0 | 72.1 | 50 | 22 | 22 | 5 | 23 | 56 | 0 | 37 | 3 | 0 | 0 | 3 | 0 | 3.43 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 82 | 0 | 5 | 1 | 3.92 | .286 | 1.20 | 8.0 | 2.9 | 9.0 | 66.2 | 59 | 31 | 29 | 7 | 21 | 66 | 0 | 0 | 3 | 0 | 0 | 0 | 3 | 3.33 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 48 | 0 | 3 | 2 | 1.88 | .250 | 0.98 | 6.4 | 2.4 | 7.9 | 48.0 | 34 | 12 | 10 | 2 | 13 | 42 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 2.67 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 82 | 0 | 5 | 0 | 4.01 | .315 | 1.34 | 7.8 | 4.3 | 8.7 | 67.1 | 58 | 31 | 30 | 5 | 32 | 65 | 0 | 0 | 1 | 0 | 0 | 3 | 5 | 3.60 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 36 | 0 | 5 | 3 | 2.74 | .269 | 1.10 | 8.1 | 1.9 | 7.3 | 42.2 | 38 | 14 | 13 | 5 | 9 | 34 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.57 |