| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 30 | 30 | 8 | 13 | 4.96 | .320 | 1.39 | 8.0 | 4.6 | 8.0 | 174.1 | 154 | 97 | 96 | 23 | 88 | 154 | 0 | 0 | 0 | 0 | 15 | 4 | 2 | 4.53 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 90 | 28 | 28 | 11 | 9 | 3.80 | .307 | 1.31 | 8.5 | 3.3 | 9.8 | 189.1 | 178 | 83 | 80 | 22 | 70 | 205 | 4 | 0 | 0 | 0 | 17 | 4 | 1 | 3.52 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 30 | 30 | 13 | 11 | 2.78 | .278 | 1.15 | 8.2 | 2.2 | 7.1 | 226.2 | 206 | 78 | 70 | 21 | 54 | 178 | 8 | 0 | 0 | 1 | 24 | 2 | 3 | 3.38 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 29 | 29 | 6 | 18 | 6.99 | .355 | 1.65 | 10.6 | 4.3 | 6.5 | 121.0 | 142 | 98 | 94 | 27 | 58 | 88 | 0 | 0 | 0 | 0 | 6 | 0 | 9 | 5.88 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 67 | 29 | 27 | 9 | 10 | 4.81 | .291 | 1.21 | 7.4 | 3.5 | 8.7 | 138.1 | 114 | 76 | 74 | 24 | 54 | 133 | 0 | 0 | 0 | 0 | 9 | 2 | 1 | 4.55 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 60 | 0 | 6 | 5 | 2.90 | .317 | 1.36 | 9.6 | 2.6 | 10.1 | 59.0 | 63 | 19 | 19 | 4 | 17 | 66 | 0 | 27 | 5 | 0 | 0 | 2 | 0 | 2.61 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 71 | 0 | 3 | 1 | 3.87 | .289 | 1.21 | 9.1 | 1.8 | 10.0 | 83.2 | 84 | 37 | 36 | 15 | 17 | 92 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 3.78 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 55 | 0 | 2 | 0 | 3.36 | .275 | 1.12 | 7.5 | 2.6 | 9.9 | 59.0 | 49 | 22 | 22 | 5 | 17 | 65 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.81 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 48 | 0 | 7 | 1 | 4.81 | .351 | 1.58 | 10.5 | 3.9 | 9.0 | 48.2 | 56 | 27 | 26 | 6 | 21 | 48 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.06 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 35 | 0 | 0 | 1 | 3.54 | .278 | 1.13 | 7.4 | 2.9 | 7.7 | 40.2 | 33 | 19 | 16 | 5 | 13 | 34 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.98 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 38 | 0 | 3 | 0 | 2.79 | .233 | 0.89 | 6.0 | 2.1 | 9.2 | 51.2 | 34 | 16 | 16 | 9 | 12 | 52 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.02 |