| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 24 | 24 | 7 | 13 | 5.34 | .340 | 1.49 | 8.4 | 5.0 | 9.6 | 143.1 | 134 | 86 | 85 | 15 | 80 | 152 | 0 | 0 | 0 | 0 | 10 | 8 | 0 | 4.08 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 82 | 23 | 23 | 13 | 6 | 3.99 | .296 | 1.25 | 8.4 | 2.8 | 9.5 | 149.0 | 139 | 66 | 66 | 19 | 47 | 157 | 1 | 0 | 0 | 0 | 13 | 2 | 2 | 3.54 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 23 | 23 | 5 | 10 | 4.49 | .345 | 1.55 | 8.5 | 5.5 | 9.4 | 108.1 | 102 | 60 | 54 | 12 | 66 | 113 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 4.27 |
| SP | Brown, K.Brown, Kevin # >> | 31 | 1996 | R | 67 | 23 | 23 | 5 | 11 | 5.17 | .311 | 1.32 | 9.0 | 2.9 | 5.8 | 148.0 | 148 | 92 | 85 | 26 | 48 | 95 | 3 | 0 | 0 | 2 | 10 | 4 | 4 | 5.05 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 63 | 0 | 5 | 3 | 4.05 | .284 | 1.17 | 7.7 | 2.8 | 9.0 | 86.2 | 74 | 41 | 39 | 16 | 27 | 86 | 0 | 5 | 5 | 0 | 0 | 2 | 0 | 4.43 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 55 | 0 | 1 | 3 | 4.55 | .313 | 1.32 | 7.5 | 4.4 | 8.9 | 61.1 | 51 | 31 | 31 | 11 | 30 | 60 | 0 | 6 | 0 | 0 | 0 | 3 | 0 | 5.00 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 49 | 37 | 0 | 1 | 1 | 5.29 | .302 | 1.28 | 7.9 | 3.7 | 10.5 | 49.1 | 43 | 30 | 29 | 4 | 20 | 57 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 3.02 |
| SP | Candelaria, J.Candelaria, John >> | 33 | 1986 | L | 54 | 2 | 0 | 0 | 0 | 3.00 | .308 | 1.33 | 9.0 | 3.0 | 3.0 | 3.0 | 3 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.33 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 25 | 0 | 4 | 6 | 5.74 | .379 | 1.79 | 10.7 | 5.4 | 7.1 | 47.0 | 56 | 34 | 30 | 10 | 28 | 37 | 0 | 0 | 2 | 0 | 0 | 2 | 3 | 6.11 |