| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 84 | 24 | 24 | 12 | 9 | 3.80 | .288 | 1.20 | 7.8 | 3.0 | 5.9 | 147.0 | 127 | 65 | 62 | 19 | 49 | 96 | 3 | 0 | 0 | 2 | 14 | 2 | 3 | 4.41 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 23 | 23 | 0 | 8 | 6.01 | .351 | 1.59 | 11.1 | 3.3 | 8.9 | 91.1 | 112 | 64 | 61 | 24 | 33 | 90 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 5.64 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 29 | 22 | 10 | 7 | 4.81 | .318 | 1.39 | 8.9 | 3.6 | 9.9 | 127.1 | 126 | 71 | 68 | 19 | 51 | 139 | 1 | 2 | 0 | 0 | 10 | 1 | 0 | 3.98 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 94 | 73 | 0 | 5 | 4 | 3.36 | .274 | 1.12 | 5.5 | 4.6 | 10.0 | 96.1 | 59 | 39 | 36 | 10 | 49 | 107 | 0 | 3 | 2 | 0 | 0 | 1 | 6 | 3.69 |
| CL | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 65 | 0 | 4 | 9 | 3.31 | .308 | 1.29 | 9.6 | 2.1 | 7.7 | 89.2 | 95 | 38 | 33 | 5 | 21 | 76 | 0 | 12 | 4 | 0 | 0 | 4 | 0 | 2.87 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 69 | 0 | 3 | 2 | 4.72 | .342 | 1.51 | 7.9 | 5.7 | 9.0 | 76.1 | 67 | 44 | 40 | 10 | 48 | 76 | 0 | 4 | 4 | 0 | 0 | 4 | 6 | 4.76 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 62 | 0 | 4 | 3 | 4.54 | .294 | 1.22 | 6.2 | 4.8 | 10.9 | 71.1 | 49 | 36 | 36 | 10 | 38 | 86 | 0 | 4 | 0 | 0 | 0 | 2 | 4 | 4.10 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 66 | 53 | 0 | 2 | 1 | 3.70 | .270 | 1.11 | 6.8 | 3.3 | 6.1 | 65.2 | 49 | 28 | 27 | 5 | 24 | 44 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 3.75 |