| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 30 | 30 | 12 | 12 | 3.82 | .264 | 1.05 | 7.7 | 1.8 | 9.5 | 198.0 | 169 | 89 | 84 | 27 | 39 | 210 | 2 | 0 | 0 | 0 | 20 | 5 | 4 | 3.32 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 29 | 29 | 8 | 10 | 5.19 | .315 | 1.36 | 8.4 | 3.9 | 8.5 | 168.1 | 156 | 98 | 97 | 28 | 73 | 158 | 2 | 0 | 0 | 0 | 15 | 3 | 5 | 4.64 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 28 | 28 | 8 | 13 | 5.78 | .366 | 1.69 | 10.8 | 4.4 | 6.0 | 151.0 | 182 | 106 | 97 | 27 | 73 | 100 | 1 | 0 | 0 | 1 | 10 | 6 | 2 | 5.57 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 70 | 22 | 19 | 7 | 9 | 4.57 | .320 | 1.39 | 8.7 | 3.9 | 6.6 | 141.2 | 136 | 74 | 72 | 18 | 61 | 104 | 5 | 0 | 0 | 0 | 8 | 3 | 2 | 4.55 |
| CL | Rhodes, A.Rhodes, Arthur # >> | 32 | 2001 | L | 62 | 40 | 0 | 5 | 2 | 5.08 | .293 | 1.24 | 8.8 | 2.5 | 10.4 | 44.1 | 43 | 25 | 25 | 10 | 12 | 51 | 0 | 0 | 1 | 0 | 0 | 0 | 5 | 4.45 |
| SU | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 52 | 15 | 0 | 0 | 0 | 1.02 | .293 | 1.25 | 7.4 | 4.2 | 9.5 | 17.2 | 14 | 2 | 2 | 1 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.06 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 64 | 54 | 0 | 8 | 1 | 5.54 | .319 | 1.40 | 9.9 | 2.8 | 9.0 | 52.0 | 57 | 32 | 32 | 10 | 16 | 52 | 0 | 1 | 4 | 0 | 0 | 0 | 1 | 4.42 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 28 | 0 | 0 | 3 | 7.90 | .369 | 1.72 | 10.3 | 5.3 | 9.7 | 27.1 | 31 | 24 | 24 | 5 | 16 | 29 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 5.15 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 40 | 0 | 1 | 0 | 3.29 | .324 | 1.43 | 7.8 | 5.2 | 11.8 | 38.1 | 33 | 15 | 14 | 3 | 22 | 50 | 0 | 3 | 0 | 0 | 0 | 0 | 4 | 3.13 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 49 | 0 | 5 | 6 | 4.36 | .281 | 1.12 | 6.3 | 3.9 | 9.2 | 53.2 | 37 | 26 | 26 | 10 | 23 | 54 | 0 | 28 | 5 | 0 | 0 | 3 | 0 | 4.89 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 27 | 9 | 6 | 4 | 5.19 | .345 | 1.56 | 8.6 | 5.6 | 9.5 | 131.2 | 125 | 79 | 76 | 21 | 81 | 138 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 4.88 |