| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 24 | 24 | 9 | 10 | 5.24 | .302 | 1.29 | 9.0 | 2.7 | 10.4 | 132.1 | 132 | 78 | 77 | 19 | 39 | 152 | 2 | 0 | 0 | 0 | 11 | 1 | 0 | 3.48 |
| SP | Buehler, W.Buehler, Walker # >> | 23 | 2018 | R | 84 | 23 | 23 | 9 | 9 | 3.81 | .286 | 1.17 | 7.3 | 3.3 | 8.9 | 134.2 | 109 | 57 | 57 | 14 | 49 | 133 | 0 | 0 | 0 | 0 | 15 | 4 | 5 | 3.56 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 24 | 23 | 8 | 8 | 4.58 | .314 | 1.36 | 8.3 | 4.0 | 7.1 | 147.1 | 135 | 76 | 75 | 21 | 65 | 116 | 3 | 0 | 0 | 0 | 10 | 2 | 6 | 4.65 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 23 | 23 | 6 | 8 | 5.66 | .350 | 1.58 | 11.0 | 3.3 | 9.8 | 119.1 | 145 | 78 | 75 | 22 | 44 | 130 | 0 | 0 | 0 | 0 | 10 | 4 | 1 | 4.43 |
| RP | Chapman, A.Chapman, Aroldis † >> | 24 | 2012 | L | 87 | 67 | 0 | 8 | 2 | 2.87 | .281 | 1.17 | 5.8 | 4.9 | 11.2 | 87.2 | 56 | 28 | 28 | 10 | 47 | 108 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 3.63 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 46 | 0 | 2 | 0 | 2.78 | .283 | 1.18 | 6.4 | 4.3 | 7.5 | 55.0 | 39 | 18 | 17 | 7 | 26 | 46 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.40 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 43 | 0 | 3 | 3 | 5.19 | .330 | 1.45 | 8.4 | 4.8 | 10.0 | 43.1 | 40 | 26 | 25 | 6 | 23 | 48 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 4.26 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 48 | 0 | 3 | 5 | 2.53 | .316 | 1.37 | 6.6 | 5.8 | 11.2 | 53.1 | 39 | 17 | 15 | 3 | 34 | 66 | 0 | 23 | 3 | 0 | 0 | 1 | 2 | 3.23 |