| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 30 | 30 | 15 | 7 | 3.11 | .255 | 1.01 | 7.1 | 2.0 | 10.8 | 196.2 | 155 | 72 | 68 | 21 | 43 | 236 | 2 | 0 | 0 | 1 | 21 | 4 | 0 | 2.70 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 92 | 29 | 29 | 14 | 8 | 4.06 | .290 | 1.21 | 8.0 | 2.9 | 9.4 | 201.2 | 179 | 95 | 91 | 33 | 65 | 209 | 7 | 0 | 0 | 1 | 18 | 3 | 1 | 4.07 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 29 | 29 | 12 | 9 | 5.50 | .337 | 1.51 | 10.3 | 3.3 | 9.3 | 180.0 | 206 | 117 | 110 | 31 | 65 | 186 | 1 | 0 | 0 | 0 | 15 | 3 | 7 | 4.31 |
| SP | Higuera, T.Higuera, Teddy † >> | 30 | 1988 | L | 65 | 29 | 27 | 19 | 5 | 4.11 | .302 | 1.27 | 8.3 | 3.1 | 7.1 | 188.1 | 174 | 91 | 86 | 31 | 65 | 148 | 2 | 1 | 0 | 0 | 14 | 5 | 0 | 4.69 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 73 | 0 | 8 | 1 | 2.96 | .298 | 1.27 | 7.2 | 4.2 | 8.7 | 85.0 | 68 | 28 | 28 | 11 | 40 | 82 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.16 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 57 | 0 | 3 | 3 | 2.51 | .259 | 1.02 | 5.6 | 3.5 | 9.0 | 61.0 | 38 | 20 | 17 | 5 | 24 | 61 | 0 | 1 | 4 | 0 | 0 | 2 | 2 | 3.34 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 40 | 0 | 3 | 0 | 3.12 | .257 | 1.04 | 6.4 | 2.9 | 8.8 | 52.0 | 37 | 18 | 18 | 6 | 17 | 51 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.52 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 56 | 0 | 2 | 4 | 2.67 | .235 | 0.89 | 4.8 | 3.3 | 9.9 | 60.2 | 32 | 18 | 18 | 8 | 22 | 66 | 0 | 32 | 5 | 0 | 0 | 2 | 6 | 3.73 |