| SP | Santana, J.Santana, Johan >> | 31 | 2004 | L | 99 | 31 | 31 | 10 | 13 | 3.49 | .288 | 1.19 | 7.6 | 3.1 | 9.5 | 209.0 | 177 | 90 | 81 | 23 | 72 | 221 | 4 | 0 | 0 | 0 | 21 | 4 | 1 | 3.41 |
| SP | Liriano, F.Liriano, Francisco >> | 27 | 2006 | L | 100 | 31 | 31 | 10 | 8 | 3.43 | .252 | 0.99 | 6.9 | 2.0 | 9.0 | 181.0 | 139 | 69 | 69 | 21 | 40 | 180 | 0 | 0 | 0 | 0 | 19 | 4 | 7 | 3.25 |
| SP | Hudson, T.Hudson, Tim # >> | 35 | 1999 | R | 76 | 30 | 30 | 9 | 14 | 4.80 | .299 | 1.25 | 8.0 | 3.2 | 6.4 | 197.0 | 175 | 108 | 105 | 32 | 71 | 140 | 8 | 0 | 0 | 1 | 17 | 6 | 4 | 4.86 |
| SP | Garza, M.Garza, Matt # >> | 27 | 2009 | R | 72 | 29 | 29 | 8 | 10 | 5.26 | .317 | 1.36 | 8.7 | 3.6 | 8.0 | 157.1 | 151 | 94 | 92 | 29 | 63 | 139 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 4.93 |
| RP | Balfour, G.Balfour, Grant >> | 33 | 2008 | R | 92 | 90 | 0 | 4 | 3 | 2.43 | .288 | 1.19 | 6.4 | 4.4 | 10.1 | 66.2 | 47 | 20 | 18 | 3 | 32 | 74 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 2.89 |
| RP | Mijares, J.Mijares, Jose >> | 26 | 2009 | L | 79 | 92 | 0 | 2 | 1 | 3.68 | .290 | 1.19 | 7.2 | 3.5 | 6.4 | 51.1 | 41 | 26 | 21 | 8 | 20 | 36 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 4.92 |
| RP | Vargas, C.Vargas, Claudio >> | 32 | 2009 | R | 83 | 39 | 0 | 4 | 6 | 3.31 | .325 | 1.42 | 8.0 | 4.9 | 5.4 | 35.1 | 31 | 14 | 13 | 4 | 19 | 21 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 5.00 |
| RP | Guerrier, M.Guerrier, Matt >> | 32 | 2009 | R | 75 | 21 | 0 | 2 | 3 | 2.39 | .218 | 0.76 | 5.2 | 1.7 | 6.2 | 26.1 | 15 | 8 | 7 | 3 | 5 | 18 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.92 |
| RP | Breslow, C.Breslow, Craig >> | 30 | 2008 | L | 70 | 60 | 0 | 2 | 0 | 1.43 | .242 | 0.96 | 4.6 | 4.1 | 7.1 | 37.2 | 19 | 7 | 6 | 1 | 17 | 29 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.16 |
| SP | Slowey, K.Slowey, Kevin >> | 26 | 2008 | R | 71 | 5 | 0 | 1 | 0 | 2.78 | .227 | 0.88 | 7.4 | 0.8 | 9.0 | 22.2 | 18 | 9 | 7 | 2 | 2 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.45 |