| SP | Weaver, J.Weaver, Jered >> | 28 | 2006 | R | 98 | 31 | 31 | 15 | 10 | 3.00 | .258 | 1.02 | 7.0 | 2.2 | 6.6 | 240.1 | 187 | 84 | 80 | 29 | 59 | 177 | 12 | 0 | 0 | 1 | 23 | 5 | 2 | 3.90 |
| SP | Vazquez, J.Vazquez, Javier # >> | 34 | 2009 | R | 87 | 31 | 31 | 13 | 11 | 4.85 | .293 | 1.20 | 8.3 | 2.5 | 9.3 | 202.1 | 187 | 110 | 109 | 34 | 55 | 209 | 1 | 0 | 0 | 1 | 11 | 9 | 3 | 4.07 |
| SP | Santana, E.Santana, Ervin # >> | 27 | 2006 | R | 84 | 30 | 30 | 12 | 11 | 4.15 | .280 | 1.14 | 7.8 | 2.5 | 6.1 | 214.2 | 185 | 103 | 99 | 27 | 59 | 144 | 6 | 0 | 0 | 0 | 15 | 6 | 7 | 4.21 |
| RP | Arredondo, J.Arredondo, Jose >> | 26 | 2008 | R | 94 | 73 | 0 | 9 | 4 | 3.67 | .294 | 1.23 | 7.4 | 3.7 | 6.1 | 81.0 | 67 | 34 | 33 | 9 | 33 | 55 | 0 | 2 | 4 | 0 | 0 | 1 | 1 | 4.35 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 32 | 2004 | L | 97 | 69 | 0 | 3 | 0 | 1.63 | .212 | 0.77 | 5.3 | 1.7 | 12.1 | 49.2 | 29 | 9 | 9 | 4 | 9 | 66 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 2.04 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2009 | R | 86 | 47 | 0 | 0 | 6 | 4.68 | .266 | 1.06 | 7.1 | 2.6 | 5.4 | 42.1 | 33 | 22 | 22 | 9 | 12 | 25 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 5.52 |
| RP | Bulger, J.Bulger, Jason >> | 32 | 2009 | R | 72 | 13 | 0 | 0 | 0 | 5.68 | .321 | 1.42 | 8.3 | 5.3 | 8.3 | 12.2 | 11 | 8 | 8 | 2 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.08 |
| CL | Rodriguez, F.Rodriguez, Francisco >> | 28 | 2003 | R | 100 | 49 | 0 | 6 | 4 | 1.34 | .193 | 0.71 | 3.9 | 2.5 | 9.7 | 73.2 | 32 | 12 | 11 | 5 | 20 | 79 | 0 | 32 | 3 | 0 | 0 | 1 | 1 | 2.59 |
| SP | Jurrjens, J.Jurrjens, Jair >> | 24 | 2009 | R | 73 | 18 | 0 | 0 | 1 | 4.56 | .309 | 1.33 | 9.0 | 3.0 | 5.3 | 73.0 | 73 | 40 | 37 | 10 | 24 | 43 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.63 |