| SP | Johnson, R.Johnson, Randy # >> | 44 | 2004 | L | 96 | 33 | 33 | 9 | 13 | 4.74 | .308 | 1.30 | 9.2 | 2.5 | 9.3 | 209.0 | 213 | 118 | 110 | 37 | 58 | 216 | 5 | 0 | 0 | 0 | 18 | 8 | 7 | 4.18 |
| SP | Martinez, R.Martinez, Ramon >> | 39 | 1989 | R | 88 | 32 | 32 | 14 | 8 | 3.08 | .267 | 1.07 | 7.2 | 2.5 | 5.8 | 219.1 | 175 | 79 | 75 | 21 | 60 | 141 | 4 | 0 | 0 | 2 | 19 | 5 | 3 | 3.85 |
| SP | Pavano, C.Pavano, Carl >> | 31 | 1998 | R | 91 | 32 | 32 | 11 | 14 | 3.95 | .299 | 1.25 | 9.1 | 2.2 | 7.9 | 193.2 | 195 | 93 | 85 | 19 | 48 | 169 | 2 | 0 | 0 | 2 | 20 | 5 | 4 | 3.35 |
| SP | Nabholz, C.Nabholz, Chris >> | 40 | 1990 | L | 83 | 31 | 31 | 10 | 12 | 4.92 | .325 | 1.41 | 8.7 | 4.0 | 5.6 | 186.2 | 180 | 115 | 102 | 20 | 83 | 115 | 0 | 0 | 0 | 0 | 14 | 7 | 4 | 4.61 |
| RP | Urbina, U.Urbina, Ugueth >> | 33 | 1998 | R | 100 | 83 | 0 | 6 | 6 | 2.50 | .271 | 1.08 | 7.3 | 2.4 | 10.1 | 119.0 | 97 | 38 | 33 | 9 | 32 | 133 | 0 | 8 | 6 | 0 | 0 | 4 | 0 | 2.66 |
| RP | Strickland, S.Strickland, Scott >> | 31 | 2000 | R | 97 | 64 | 0 | 6 | 6 | 2.69 | .273 | 1.08 | 7.3 | 2.4 | 9.0 | 87.0 | 71 | 29 | 26 | 14 | 23 | 87 | 0 | 8 | 4 | 0 | 0 | 4 | 1 | 4.02 |
| RP | Zambrano, V.Zambrano, Victor >> | 32 | 2001 | R | 93 | 12 | 0 | 0 | 4 | 3.38 | .310 | 1.35 | 4.2 | 8.3 | 9.7 | 13.1 | 6 | 5 | 5 | 0 | 12 | 14 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 3.62 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 92 | 13 | 0 | 0 | 0 | 5.40 | .314 | 1.37 | 8.2 | 4.9 | 9.8 | 11.2 | 10 | 7 | 7 | 1 | 6 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.64 |
| RP | Cordero, C.Cordero, Chad # >> | 25 | 2005 | R | 87 | 25 | 0 | 0 | 1 | 6.48 | .291 | 1.20 | 8.2 | 2.7 | 6.3 | 33.1 | 30 | 25 | 24 | 3 | 10 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.79 |
| SP | Moss, D.Moss, Damian # >> | 31 | 2002 | L | 75 | 19 | 0 | 3 | 3 | 4.15 | .287 | 1.20 | 7.2 | 3.6 | 6.7 | 91.0 | 73 | 52 | 42 | 13 | 36 | 68 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 4.58 |