| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 26 | 26 | 7 | 12 | 4.60 | .302 | 1.28 | 8.6 | 2.8 | 7.6 | 174.0 | 167 | 90 | 89 | 28 | 55 | 146 | 1 | 0 | 0 | 0 | 14 | 4 | 2 | 4.43 |
| SP | Hamels, C.Hamels, Cole # >> | 25 | 2008 | L | 72 | 25 | 25 | 4 | 14 | 5.66 | .332 | 1.44 | 9.9 | 3.1 | 5.4 | 157.1 | 173 | 112 | 99 | 41 | 54 | 94 | 3 | 0 | 0 | 1 | 9 | 8 | 0 | 6.38 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 53 | 25 | 25 | 3 | 14 | 6.34 | .347 | 1.56 | 10.8 | 3.3 | 6.0 | 143.1 | 172 | 105 | 101 | 31 | 52 | 95 | 2 | 0 | 0 | 1 | 8 | 4 | 5 | 5.66 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 25 | 25 | 9 | 9 | 7.02 | .364 | 1.67 | 11.6 | 3.5 | 6.5 | 142.1 | 183 | 115 | 111 | 22 | 55 | 102 | 3 | 0 | 0 | 0 | 10 | 6 | 12 | 4.87 |
| SP | Beckett, J.Beckett, Josh # >> | 27 | 2007 | R | 48 | 25 | 25 | 7 | 13 | 5.18 | .323 | 1.41 | 10.0 | 2.6 | 7.5 | 158.0 | 176 | 91 | 91 | 37 | 46 | 132 | 2 | 0 | 0 | 2 | 9 | 4 | 5 | 5.32 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 75 | 64 | 0 | 4 | 5 | 4.12 | .324 | 1.43 | 8.5 | 4.4 | 7.3 | 74.1 | 70 | 34 | 34 | 7 | 36 | 60 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 4.11 |
| RP | Timlin, M.Timlin, Mike >> | 36 | 2002 | R | 50 | 55 | 0 | 5 | 4 | 4.10 | .315 | 1.34 | 10.1 | 2.1 | 6.2 | 74.2 | 83 | 37 | 34 | 10 | 17 | 51 | 0 | 6 | 2 | 0 | 0 | 3 | 2 | 4.19 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 35 | 37 | 0 | 2 | 1 | 2.98 | .303 | 1.24 | 7.4 | 3.8 | 10.0 | 45.1 | 37 | 15 | 15 | 4 | 19 | 50 | 0 | 6 | 2 | 0 | 0 | 3 | 1 | 3.40 |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2008 | R | 39 | 13 | 0 | 0 | 1 | 5.32 | .377 | 1.77 | 11.5 | 4.5 | 8.2 | 22.0 | 28 | 13 | 13 | 6 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.36 |