| SP | Schilling, C.Schilling, Curt $$ >> | 36 | 2002 | R | 93 | 10 | 10 | 3 | 6 | 5.06 | .333 | 1.47 | 10.5 | 2.9 | 9.1 | 74.2 | 86 | 47 | 42 | 16 | 24 | 75 | 2 | 0 | 0 | 0 | 3 | 2 | 2 | 4.84 |
| SP | Wakefield, T.Wakefield, Tim $ >> | 36 | 2002 | R | 86 | 10 | 10 | 3 | 2 | 3.38 | .295 | 1.24 | 6.5 | 4.8 | 6.3 | 53.1 | 38 | 20 | 20 | 6 | 28 | 37 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.72 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 76 | 9 | 9 | 6 | 1 | 3.02 | .284 | 1.19 | 7.8 | 3.1 | 8.2 | 59.2 | 51 | 20 | 20 | 7 | 20 | 54 | 2 | 0 | 0 | 1 | 6 | 0 | 1 | 3.73 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 89 | 27 | 0 | 1 | 0 | 3.52 | .276 | 1.14 | 5.4 | 5.1 | 7.8 | 30.2 | 18 | 12 | 12 | 4 | 17 | 26 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.70 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 86 | 23 | 0 | 1 | 2 | 4.55 | .307 | 1.26 | 9.3 | 2.3 | 8.1 | 31.2 | 32 | 16 | 16 | 6 | 8 | 28 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 4.68 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 22 | 0 | 2 | 0 | 2.77 | .271 | 1.08 | 6.9 | 2.8 | 9.7 | 26.0 | 20 | 8 | 8 | 1 | 8 | 28 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 2.38 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 68 | 11 | 0 | 0 | 2 | 4.02 | .266 | 1.09 | 7.8 | 2.4 | 13.8 | 15.2 | 13 | 7 | 7 | 3 | 4 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 77 | 18 | 0 | 3 | 2 | 8.31 | .366 | 1.67 | 10.1 | 5.3 | 10.6 | 17.1 | 19 | 17 | 16 | 6 | 10 | 20 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 7.18 |
| CL | Gagne, E.Gagne, Eric $ >> | 27 | 2003 | R | 100 | 19 | 0 | 4 | 0 | 0.89 | .202 | 0.73 | 4.2 | 2.4 | 8.7 | 30.1 | 14 | 4 | 3 | 2 | 8 | 29 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 2.83 |