| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 7 | 7 | 4 | 3 | 3.38 | .273 | 1.05 | 5.8 | 3.7 | 9.7 | 53.1 | 34 | 20 | 20 | 8 | 22 | 57 | 4 | 0 | 0 | 2 | 3 | 4 | 2 | 4.28 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 86 | 7 | 7 | 3 | 2 | 4.50 | .377 | 1.71 | 11.8 | 3.6 | 8.8 | 38.0 | 50 | 20 | 19 | 5 | 15 | 37 | 0 | 0 | 0 | 0 | 3 | 4 | 0 | 4.26 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 67 | 7 | 7 | 1 | 1 | 10.90 | .447 | 2.37 | 18.5 | 3.2 | 5.3 | 17.1 | 35 | 21 | 21 | 4 | 6 | 10 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.12 |
| RP | Betancourt, R.Betancourt, Rafael $ >> | 32 | 2007 | R | 87 | 18 | 0 | 4 | 0 | 2.27 | .202 | 0.76 | 5.8 | 1.2 | 9.0 | 31.2 | 20 | 10 | 8 | 4 | 4 | 31 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 3.06 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 90 | 18 | 0 | 1 | 1 | 4.05 | .355 | 1.60 | 9.9 | 4.5 | 9.0 | 20.0 | 22 | 10 | 9 | 4 | 10 | 20 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 5.25 |
| RP | Groom, B.Groom, Buddy $ >> | 37 | 2002 | L | 62 | 15 | 0 | 1 | 0 | 0.78 | .233 | 0.91 | 5.5 | 2.7 | 5.5 | 23.0 | 14 | 4 | 2 | 1 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.26 |
| RP | Corpas, M.Corpas, Manuel >> | 25 | 2007 | R | 26 | 14 | 0 | 1 | 1 | 5.40 | .357 | 1.53 | 10.8 | 3.0 | 8.4 | 15.0 | 18 | 9 | 9 | 2 | 5 | 14 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.27 |
| SP | Bonderman, J.Bonderman, Jeremy >> | 24 | 2006 | R | 7 | 9 | 7 | 1 | 2 | 4.85 | .333 | 1.50 | 10.3 | 3.4 | 6.2 | 42.2 | 48 | 26 | 23 | 9 | 16 | 29 | 0 | 1 | 0 | 0 | 3 | 0 | 0 | 5.55 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 81 | 10 | 0 | 2 | 1 | 3.98 | .312 | 1.29 | 8.7 | 3.2 | 5.2 | 31.2 | 30 | 15 | 14 | 6 | 11 | 18 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 5.61 |