| SP | Duchscherer, J.Duchscherer, Justin # >> | 31 | 2008 | R | 84 | 10 | 10 | 7 | 1 | 2.92 | .258 | 1.03 | 6.6 | 2.7 | 5.7 | 71.0 | 52 | 25 | 23 | 11 | 21 | 45 | 3 | 0 | 0 | 1 | 6 | 1 | 0 | 4.68 |
| SP | Loaiza, E.Loaiza, Esteban # >> | 32 | 2003 | R | 58 | 9 | 9 | 5 | 3 | 3.90 | .272 | 1.09 | 7.8 | 2.0 | 7.7 | 62.1 | 54 | 28 | 27 | 12 | 14 | 53 | 1 | 0 | 0 | 1 | 5 | 2 | 1 | 4.58 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 98 | 9 | 3 | 0 | 0 | 5.30 | .325 | 1.42 | 9.2 | 3.6 | 8.3 | 37.1 | 38 | 22 | 22 | 6 | 15 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.57 |
| SP | Carpenter, C.Carpenter, Chris # >> | 34 | 2009 | R | 79 | 10 | 10 | 4 | 3 | 5.78 | .327 | 1.44 | 10.7 | 2.3 | 6.0 | 62.1 | 74 | 43 | 40 | 15 | 16 | 41 | 1 | 0 | 0 | 0 | 3 | 1 | 1 | 5.65 |
| SP | Mussina, M.Mussina, Mike # >> | 33 | 2001 | R | 68 | 9 | 8 | 4 | 2 | 5.47 | .312 | 1.34 | 9.5 | 2.7 | 5.8 | 54.1 | 57 | 33 | 33 | 9 | 16 | 35 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 4.81 |
| CL | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 59 | 16 | 0 | 1 | 0 | 1.23 | .241 | 0.82 | 4.5 | 3.2 | 11.6 | 14.2 | 7 | 2 | 2 | 0 | 5 | 18 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 1.93 |
| SU | Springer, R.Springer, Russ >> | 39 | 2007 | R | 78 | 17 | 0 | 0 | 1 | 1.45 | .282 | 1.18 | 8.0 | 3.0 | 8.5 | 18.2 | 16 | 7 | 3 | 1 | 6 | 17 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 88 | 17 | 0 | 2 | 0 | 1.53 | .254 | 1.02 | 6.9 | 2.6 | 9.0 | 17.2 | 13 | 3 | 3 | 0 | 5 | 17 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 1.88 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 84 | 9 | 0 | 1 | 2 | 4.82 | .300 | 1.29 | 6.0 | 6.0 | 10.0 | 9.1 | 6 | 5 | 5 | 2 | 6 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.67 |