| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 31 | 31 | 14 | 10 | 3.79 | .285 | 1.18 | 7.3 | 3.4 | 7.7 | 216.1 | 174 | 91 | 91 | 32 | 82 | 184 | 3 | 0 | 0 | 1 | 17 | 3 | 11 | 4.40 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 31 | 31 | 11 | 12 | 4.68 | .322 | 1.39 | 9.7 | 2.8 | 3.7 | 219.1 | 237 | 119 | 114 | 23 | 67 | 89 | 3 | 0 | 0 | 1 | 13 | 9 | 2 | 4.59 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 30 | 30 | 14 | 12 | 4.47 | .317 | 1.36 | 9.2 | 3.1 | 7.4 | 199.1 | 203 | 101 | 99 | 36 | 68 | 164 | 4 | 0 | 0 | 1 | 17 | 6 | 1 | 4.82 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 29 | 29 | 14 | 8 | 4.45 | .307 | 1.29 | 8.4 | 3.2 | 3.9 | 196.1 | 184 | 102 | 97 | 23 | 69 | 85 | 1 | 0 | 0 | 0 | 18 | 8 | 3 | 4.84 |
| CL | Soriano, R.Soriano, Rafael † >> | 24 | 2003 | R | 85 | 53 | 0 | 3 | 4 | 3.79 | .284 | 1.17 | 7.5 | 3.2 | 8.7 | 54.2 | 45 | 23 | 23 | 9 | 19 | 52 | 0 | 32 | 4 | 0 | 0 | 1 | 0 | 4.35 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 79 | 35 | 0 | 3 | 5 | 4.85 | .293 | 1.22 | 7.5 | 3.6 | 6.9 | 42.2 | 35 | 25 | 23 | 6 | 17 | 32 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 4.62 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 40 | 0 | 1 | 1 | 5.23 | .303 | 1.28 | 8.6 | 3.1 | 3.7 | 41.1 | 39 | 26 | 24 | 8 | 14 | 17 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 5.80 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 45 | 0 | 0 | 2 | 4.15 | .307 | 1.31 | 8.0 | 3.8 | 9.2 | 52.0 | 46 | 25 | 24 | 3 | 22 | 53 | 0 | 0 | 2 | 0 | 0 | 1 | 3 | 3.04 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 18 | 5 | 3 | 3 | 6.46 | .328 | 1.36 | 9.3 | 2.9 | 7.5 | 78.0 | 81 | 57 | 56 | 18 | 25 | 65 | 0 | 0 | 0 | 0 | 1 | 8 | 0 | 5.60 |