| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 11 | 11 | 4 | 4 | 4.86 | .324 | 1.42 | 9.8 | 3.1 | 8.2 | 70.1 | 76 | 38 | 38 | 12 | 24 | 64 | 1 | 0 | 0 | 1 | 4 | 1 | 2 | 4.47 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 11 | 11 | 3 | 6 | 3.31 | .262 | 1.03 | 7.2 | 2.1 | 5.0 | 81.2 | 65 | 32 | 30 | 8 | 19 | 45 | 5 | 0 | 0 | 1 | 7 | 3 | 1 | 3.99 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 10 | 10 | 2 | 5 | 4.81 | .341 | 1.51 | 10.4 | 3.3 | 4.0 | 63.2 | 73 | 39 | 34 | 7 | 23 | 28 | 2 | 0 | 0 | 0 | 6 | 3 | 2 | 4.79 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 11 | 10 | 3 | 4 | 5.31 | .338 | 1.52 | 11.0 | 2.7 | 6.4 | 59.1 | 72 | 35 | 35 | 8 | 18 | 42 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 4.31 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 23 | 0 | 0 | 3 | 5.64 | .362 | 1.70 | 9.8 | 5.7 | 10.2 | 22.1 | 24 | 14 | 14 | 5 | 14 | 25 | 0 | 8 | 2 | 0 | 0 | 0 | 0 | 5.59 |
| SU | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 24 | 0 | 2 | 1 | 9.45 | .429 | 2.20 | 12.2 | 7.7 | 10.8 | 20.0 | 27 | 21 | 21 | 4 | 17 | 24 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.90 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 26 | 0 | 1 | 0 | 3.03 | .305 | 1.28 | 7.4 | 4.3 | 7.8 | 29.2 | 24 | 14 | 10 | 5 | 14 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.07 |