| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 20 | 20 | 4 | 9 | 5.01 | .319 | 1.37 | 9.8 | 2.7 | 9.0 | 118.2 | 128 | 71 | 66 | 21 | 35 | 118 | 1 | 0 | 0 | 0 | 9 | 4 | 0 | 4.31 |
| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 20 | 20 | 9 | 8 | 5.44 | .326 | 1.43 | 9.4 | 3.5 | 5.4 | 124.0 | 129 | 76 | 75 | 17 | 48 | 74 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 4.82 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 20 | 20 | 9 | 7 | 4.88 | .332 | 1.45 | 9.1 | 4.0 | 8.7 | 118.0 | 119 | 67 | 64 | 17 | 52 | 114 | 0 | 0 | 0 | 0 | 12 | 5 | 1 | 4.39 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 20 | 17 | 4 | 5 | 4.58 | .319 | 1.38 | 9.4 | 3.0 | 3.6 | 114.0 | 119 | 66 | 58 | 11 | 38 | 46 | 1 | 0 | 0 | 0 | 9 | 3 | 2 | 4.53 |
| CL | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 41 | 0 | 0 | 7 | 4.20 | .304 | 1.29 | 8.4 | 3.2 | 8.6 | 45.0 | 42 | 22 | 21 | 8 | 16 | 43 | 0 | 16 | 4 | 0 | 0 | 1 | 1 | 4.53 |
| SU | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 43 | 0 | 1 | 5 | 5.37 | .294 | 1.25 | 7.5 | 3.8 | 8.3 | 55.1 | 46 | 33 | 33 | 14 | 23 | 51 | 0 | 5 | 5 | 0 | 0 | 0 | 1 | 5.71 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 45 | 0 | 2 | 3 | 5.27 | .382 | 1.83 | 9.0 | 7.7 | 10.9 | 42.2 | 42 | 30 | 25 | 4 | 36 | 51 | 0 | 0 | 4 | 0 | 0 | 1 | 3 | 4.45 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 53 | 39 | 0 | 1 | 2 | 3.25 | .304 | 1.29 | 7.8 | 4.0 | 6.4 | 52.2 | 45 | 20 | 19 | 2 | 23 | 37 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.46 |