| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 21 | 21 | 10 | 4 | 2.85 | .278 | 1.15 | 7.8 | 2.5 | 5.6 | 145.1 | 126 | 47 | 46 | 8 | 41 | 91 | 3 | 0 | 0 | 3 | 16 | 1 | 3 | 3.33 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 21 | 21 | 10 | 8 | 3.26 | .339 | 1.50 | 7.4 | 6.1 | 7.2 | 127.0 | 104 | 56 | 46 | 10 | 86 | 101 | 1 | 0 | 0 | 1 | 12 | 5 | 1 | 4.58 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 20 | 20 | 5 | 5 | 5.48 | .335 | 1.51 | 8.0 | 5.7 | 9.0 | 95.1 | 84 | 61 | 58 | 16 | 60 | 95 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 5.08 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 61 | 0 | 5 | 0 | 1.85 | .233 | 0.90 | 6.0 | 2.1 | 7.1 | 68.0 | 45 | 15 | 14 | 4 | 16 | 54 | 0 | 3 | 0 | 0 | 0 | 1 | 3 | 2.93 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 58 | 0 | 4 | 2 | 2.09 | .223 | 0.83 | 4.8 | 2.7 | 9.2 | 73.1 | 39 | 18 | 17 | 7 | 22 | 75 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.18 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 49 | 0 | 3 | 3 | 2.50 | .232 | 0.85 | 5.3 | 2.3 | 8.5 | 54.0 | 32 | 15 | 15 | 5 | 14 | 51 | 0 | 9 | 2 | 0 | 0 | 3 | 1 | 3.26 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 38 | 0 | 2 | 2 | 3.49 | .331 | 1.48 | 7.7 | 5.8 | 9.6 | 28.1 | 24 | 12 | 11 | 2 | 18 | 30 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.71 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 33 | 0 | 2 | 2 | 4.22 | .317 | 1.39 | 7.5 | 5.2 | 7.2 | 59.2 | 49 | 34 | 28 | 8 | 34 | 47 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.90 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 43 | 11 | 0 | 0 | 3 | 4.85 | .371 | 1.69 | 8.3 | 6.9 | 10.4 | 13.0 | 12 | 8 | 7 | 2 | 10 | 15 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.23 |