| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 21 | 21 | 7 | 7 | 4.34 | .300 | 1.28 | 9.3 | 2.3 | 5.1 | 143.0 | 147 | 73 | 69 | 24 | 36 | 81 | 3 | 0 | 0 | 0 | 11 | 1 | 4 | 4.83 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 20 | 20 | 12 | 5 | 3.40 | .293 | 1.20 | 8.8 | 2.0 | 4.8 | 148.1 | 145 | 61 | 56 | 11 | 33 | 79 | 7 | 0 | 0 | 1 | 14 | 6 | 3 | 3.69 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 84 | 56 | 0 | 8 | 0 | 2.66 | .226 | 0.87 | 6.1 | 1.8 | 8.8 | 74.1 | 50 | 22 | 22 | 7 | 15 | 72 | 0 | 9 | 3 | 0 | 0 | 0 | 1 | 2.89 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 77 | 41 | 0 | 3 | 3 | 5.12 | .314 | 1.37 | 10.2 | 2.1 | 7.8 | 51.0 | 58 | 29 | 29 | 10 | 12 | 44 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 4.53 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 28 | 0 | 1 | 1 | 3.38 | .314 | 1.34 | 10.1 | 2.0 | 8.2 | 32.0 | 36 | 13 | 12 | 4 | 7 | 29 | 0 | 6 | 0 | 0 | 0 | 1 | 1 | 3.56 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 12 | 0 | 1 | 0 | 1.23 | .228 | 0.89 | 5.8 | 2.6 | 8.4 | 14.2 | 9 | 2 | 2 | 1 | 4 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.93 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 13 | 0 | 0 | 0 | 2.18 | .225 | 0.87 | 6.8 | 1.4 | 5.4 | 20.2 | 15 | 5 | 5 | 1 | 3 | 12 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2.90 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 5 | 2 | 2 | 2 | 5.14 | .315 | 1.38 | 10.7 | 1.7 | 6.0 | 21.0 | 25 | 14 | 12 | 5 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |