| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 11 | 11 | 4 | 4 | 4.26 | .307 | 1.29 | 9.1 | 2.6 | 5.9 | 63.1 | 64 | 34 | 30 | 8 | 18 | 41 | 1 | 0 | 0 | 0 | 6 | 2 | 1 | 4.30 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 11 | 11 | 5 | 4 | 4.22 | .319 | 1.38 | 10.3 | 2.2 | 7.3 | 74.2 | 85 | 37 | 35 | 11 | 18 | 60 | 1 | 0 | 0 | 0 | 7 | 2 | 0 | 4.12 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 10 | 10 | 4 | 0 | 2.64 | .298 | 1.26 | 9.6 | 1.8 | 5.3 | 61.1 | 65 | 20 | 18 | 7 | 12 | 36 | 0 | 0 | 0 | 0 | 8 | 1 | 0 | 3.95 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 28 | 0 | 2 | 1 | 3.66 | .285 | 1.19 | 8.5 | 2.3 | 7.2 | 39.1 | 37 | 16 | 16 | 6 | 10 | 31 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.18 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 24 | 0 | 4 | 2 | 4.18 | .254 | 0.99 | 7.3 | 1.7 | 9.3 | 32.1 | 26 | 17 | 15 | 5 | 6 | 33 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 3.63 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 24 | 0 | 0 | 2 | 2.90 | .279 | 1.16 | 5.8 | 4.6 | 9.6 | 31.0 | 20 | 10 | 10 | 4 | 16 | 33 | 0 | 3 | 1 | 0 | 0 | 0 | 3 | 4.10 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 16 | 0 | 2 | 2 | 2.16 | .227 | 0.88 | 4.7 | 3.2 | 9.7 | 25.0 | 13 | 6 | 6 | 2 | 9 | 27 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 2.96 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 10 | 0 | 0 | 0 | 2.25 | .158 | 0.56 | 4.5 | 0.6 | 9.0 | 16.0 | 8 | 4 | 4 | 1 | 1 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 12 | 0 | 0 | 1 | 5.84 | .362 | 1.70 | 12.0 | 3.8 | 7.5 | 12.1 | 16 | 9 | 8 | 2 | 5 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.75 |