| SP | Martinez, P.Martinez, Pedro † # >> | 29 | 2000 | R | 100 | 21 | 21 | 10 | 6 | 3.00 | .219 | 0.83 | 6.1 | 1.3 | 9.6 | 168.0 | 114 | 61 | 56 | 19 | 25 | 180 | 8 | 0 | 0 | 4 | 13 | 2 | 0 | 2.81 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 20 | 20 | 6 | 10 | 3.99 | .284 | 1.15 | 8.0 | 2.4 | 8.5 | 140.0 | 124 | 63 | 62 | 20 | 37 | 132 | 4 | 0 | 0 | 1 | 12 | 6 | 2 | 3.89 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 21 | 20 | 7 | 9 | 5.74 | .345 | 1.55 | 10.4 | 3.6 | 5.5 | 133.1 | 154 | 89 | 85 | 20 | 53 | 81 | 3 | 0 | 0 | 0 | 7 | 4 | 0 | 5.02 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 55 | 0 | 1 | 2 | 4.54 | .313 | 1.32 | 8.6 | 3.4 | 11.6 | 67.1 | 64 | 36 | 34 | 11 | 25 | 86 | 0 | 8 | 3 | 0 | 0 | 3 | 2 | 3.82 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 39 | 0 | 2 | 5 | 4.28 | .286 | 1.16 | 7.1 | 3.4 | 8.6 | 48.1 | 38 | 25 | 23 | 6 | 18 | 46 | 0 | 4 | 2 | 0 | 0 | 2 | 3 | 3.96 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 32 | 0 | 2 | 3 | 4.45 | .317 | 1.39 | 8.4 | 4.2 | 10.4 | 32.1 | 30 | 16 | 16 | 3 | 15 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 18 | 0 | 0 | 0 | 2.79 | .301 | 1.24 | 7.1 | 4.3 | 12.8 | 19.1 | 15 | 6 | 6 | 3 | 9 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.79 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 4 | 0 | 0 | 1 | 7.30 | .339 | 1.54 | 11.3 | 3.0 | 6.0 | 12.1 | 15 | 11 | 10 | 4 | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.00 |