| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 31 | 31 | 8 | 16 | 4.20 | .291 | 1.22 | 7.7 | 3.2 | 8.2 | 223.0 | 191 | 111 | 104 | 33 | 80 | 203 | 4 | 0 | 0 | 0 | 17 | 3 | 8 | 4.22 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 31 | 31 | 13 | 12 | 4.34 | .317 | 1.36 | 8.8 | 3.4 | 4.9 | 228.1 | 224 | 121 | 110 | 26 | 87 | 125 | 4 | 0 | 0 | 2 | 16 | 7 | 7 | 4.62 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 30 | 30 | 4 | 23 | 6.81 | .349 | 1.59 | 10.8 | 3.6 | 5.0 | 195.2 | 233 | 153 | 148 | 38 | 79 | 109 | 4 | 0 | 0 | 1 | 8 | 3 | 8 | 5.68 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 30 | 30 | 11 | 14 | 4.02 | .289 | 1.19 | 7.8 | 2.9 | 4.4 | 239.1 | 208 | 115 | 107 | 27 | 78 | 118 | 14 | 0 | 0 | 0 | 15 | 6 | 3 | 4.54 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 30 | 30 | 9 | 16 | 4.36 | .301 | 1.26 | 8.9 | 2.4 | 4.7 | 196.0 | 194 | 108 | 95 | 18 | 52 | 102 | 1 | 0 | 0 | 0 | 14 | 7 | 2 | 4.06 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 79 | 0 | 3 | 6 | 3.91 | .311 | 1.34 | 8.4 | 3.7 | 9.8 | 99.0 | 92 | 44 | 43 | 10 | 41 | 108 | 0 | 6 | 5 | 0 | 0 | 1 | 0 | 3.40 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 67 | 0 | 3 | 5 | 3.01 | .290 | 1.20 | 8.3 | 2.6 | 8.3 | 80.2 | 74 | 33 | 27 | 8 | 23 | 74 | 0 | 7 | 3 | 0 | 0 | 2 | 1 | 3.39 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 42 | 0 | 1 | 2 | 3.02 | .292 | 1.20 | 6.5 | 4.4 | 8.2 | 47.2 | 34 | 16 | 16 | 2 | 23 | 43 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.32 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 2 | 1 | 0 | 0 | 4.82 | .263 | 0.96 | 6.0 | 3.0 | 2.0 | 9.1 | 6 | 5 | 5 | 2 | 3 | 2 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.78 |