| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 8 | 8 | 3 | 3 | 3.13 | .290 | 1.18 | 7.8 | 2.9 | 8.6 | 60.1 | 52 | 23 | 21 | 6 | 19 | 57 | 3 | 0 | 0 | 1 | 5 | 3 | 1 | 3.50 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 8 | 8 | 5 | 1 | 3.05 | .259 | 1.02 | 6.5 | 2.6 | 4.4 | 65.0 | 47 | 23 | 22 | 6 | 19 | 32 | 4 | 0 | 0 | 1 | 4 | 2 | 0 | 4.18 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 8 | 8 | 1 | 4 | 6.00 | .336 | 1.46 | 9.3 | 3.8 | 4.8 | 54.0 | 56 | 36 | 36 | 7 | 23 | 29 | 0 | 0 | 0 | 0 | 2 | 3 | 2 | 5.06 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 8 | 8 | 4 | 3 | 5.37 | .353 | 1.59 | 9.6 | 4.8 | 5.0 | 58.2 | 62 | 38 | 35 | 10 | 31 | 32 | 1 | 0 | 0 | 0 | 1 | 3 | 4 | 5.90 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 20 | 0 | 2 | 1 | 1.46 | .204 | 0.73 | 3.8 | 3.0 | 9.4 | 24.2 | 10 | 4 | 4 | 1 | 8 | 25 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 2.58 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 13 | 0 | 0 | 1 | 4.02 | .319 | 1.40 | 9.0 | 4.2 | 10.2 | 15.2 | 15 | 9 | 7 | 3 | 7 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.73 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 12 | 0 | 1 | 1 | 3.95 | .328 | 1.39 | 10.4 | 2.8 | 6.2 | 13.2 | 15 | 7 | 6 | 3 | 4 | 9 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.77 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 54 | 2 | 0 | 0 | 0 | 13.50 | .500 | 3.00 | 27.0 | 0.0 | 4.5 | 2.0 | 6 | 3 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |