| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 7 | 7 | 2 | 5 | 5.54 | .336 | 1.48 | 10.4 | 2.9 | 7.6 | 52.0 | 60 | 38 | 32 | 14 | 17 | 44 | 2 | 0 | 0 | 0 | 1 | 2 | 0 | 5.90 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 7 | 7 | 3 | 1 | 4.61 | .339 | 1.49 | 10.5 | 2.9 | 7.0 | 41.0 | 48 | 21 | 21 | 4 | 13 | 32 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 3.80 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 73 | 6 | 6 | 3 | 2 | 4.35 | .299 | 1.28 | 8.8 | 2.9 | 4.4 | 41.1 | 40 | 24 | 20 | 7 | 13 | 20 | 1 | 0 | 0 | 0 | 3 | 0 | 1 | 5.20 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 6 | 6 | 1 | 4 | 4.96 | .340 | 1.52 | 10.6 | 3.2 | 6.0 | 45.1 | 53 | 25 | 25 | 6 | 16 | 30 | 2 | 0 | 0 | 0 | 2 | 1 | 1 | 4.53 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 18 | 0 | 0 | 1 | 4.98 | .261 | 1.06 | 6.4 | 3.4 | 8.1 | 21.2 | 15 | 12 | 12 | 3 | 8 | 19 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 4.19 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 9 | 0 | 0 | 1 | 2.84 | .269 | 1.11 | 6.8 | 3.8 | 7.5 | 12.2 | 9 | 5 | 4 | 1 | 5 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.67 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 12 | 0 | 0 | 1 | 11.68 | .456 | 2.51 | 16.5 | 6.8 | 9.8 | 12.1 | 22 | 20 | 16 | 5 | 9 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 8.50 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 57 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 9.0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |