| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 25 | 25 | 13 | 7 | 3.20 | .271 | 1.08 | 7.6 | 2.2 | 9.1 | 163.1 | 137 | 65 | 58 | 20 | 40 | 164 | 0 | 0 | 0 | 0 | 19 | 5 | 0 | 3.41 |
| SP | Gibson, B.Gibson, Bob † >> | 33 | 1968 | R | 93 | 25 | 25 | 14 | 6 | 3.53 | .272 | 1.10 | 6.8 | 3.1 | 4.3 | 198.2 | 150 | 84 | 78 | 15 | 69 | 94 | 11 | 0 | 0 | 4 | 14 | 4 | 3 | 4.14 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 25 | 25 | 9 | 8 | 4.73 | .309 | 1.34 | 9.4 | 2.7 | 7.9 | 177.0 | 184 | 95 | 93 | 25 | 54 | 155 | 2 | 0 | 0 | 0 | 14 | 0 | 2 | 4.00 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 20 | 20 | 11 | 7 | 4.00 | .299 | 1.25 | 7.9 | 3.4 | 5.1 | 153.0 | 135 | 71 | 68 | 22 | 57 | 87 | 8 | 0 | 0 | 2 | 9 | 4 | 1 | 4.93 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 72 | 0 | 4 | 1 | 2.91 | .261 | 1.06 | 5.7 | 4.0 | 11.3 | 43.1 | 27 | 14 | 14 | 5 | 19 | 54 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 74 | 0 | 3 | 0 | 2.08 | .244 | 0.90 | 5.4 | 2.7 | 10.5 | 43.1 | 26 | 10 | 10 | 5 | 13 | 50 | 0 | 7 | 2 | 0 | 0 | 3 | 1 | 3.30 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 56 | 0 | 4 | 1 | 2.38 | .251 | 0.96 | 6.4 | 2.4 | 5.3 | 41.2 | 29 | 12 | 11 | 2 | 11 | 24 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 3.41 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 31 | 0 | 3 | 2 | 2.61 | .262 | 1.06 | 5.9 | 4.1 | 7.7 | 20.2 | 13 | 7 | 6 | 1 | 9 | 17 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.30 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 11 | 2 | 2 | 3 | 3.79 | .296 | 1.18 | 9.0 | 1.8 | 8.0 | 35.2 | 35 | 15 | 15 | 6 | 7 | 31 | 0 | 0 | 0 | 0 | 1 | 3 | 1 | 4.31 |