| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 17 | 17 | 8 | 6 | 3.18 | .258 | 1.02 | 7.5 | 1.6 | 9.1 | 116.0 | 97 | 43 | 41 | 17 | 21 | 117 | 0 | 0 | 0 | 0 | 12 | 3 | 0 | 3.51 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 17 | 17 | 4 | 8 | 4.70 | .310 | 1.33 | 9.1 | 2.9 | 8.4 | 103.1 | 104 | 56 | 54 | 18 | 33 | 96 | 2 | 0 | 0 | 1 | 8 | 2 | 2 | 4.43 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 76 | 16 | 16 | 1 | 10 | 7.58 | .356 | 1.63 | 12.5 | 2.3 | 5.8 | 86.2 | 119 | 75 | 73 | 28 | 22 | 55 | 2 | 0 | 0 | 0 | 4 | 3 | 2 | 6.83 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 16 | 16 | 6 | 4 | 5.75 | .354 | 1.61 | 11.3 | 3.3 | 6.4 | 87.2 | 109 | 66 | 56 | 12 | 32 | 62 | 0 | 0 | 0 | 0 | 4 | 3 | 2 | 4.57 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 16 | 16 | 3 | 9 | 7.16 | .365 | 1.71 | 12.0 | 3.6 | 8.4 | 81.2 | 108 | 69 | 65 | 11 | 32 | 76 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 4.11 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 43 | 0 | 2 | 2 | 3.12 | .264 | 1.08 | 7.4 | 2.3 | 7.1 | 52.0 | 43 | 21 | 18 | 8 | 13 | 41 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 26 | 0 | 2 | 1 | 3.79 | .278 | 1.16 | 6.2 | 4.3 | 11.1 | 38.0 | 26 | 16 | 16 | 3 | 18 | 47 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 2.97 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 27 | 0 | 4 | 1 | 3.46 | .290 | 1.20 | 8.3 | 2.6 | 6.1 | 41.2 | 38 | 19 | 16 | 5 | 12 | 28 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 4.17 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 36 | 0 | 0 | 2 | 4.02 | .313 | 1.34 | 8.3 | 3.8 | 5.4 | 40.1 | 37 | 18 | 18 | 5 | 17 | 24 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.78 |