| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 8 | 8 | 3 | 4 | 4.06 | .290 | 1.21 | 8.7 | 2.2 | 6.1 | 62.0 | 60 | 29 | 28 | 10 | 15 | 42 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 4.52 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 7 | 7 | 3 | 2 | 4.56 | .264 | 1.06 | 8.6 | 1.0 | 4.2 | 47.1 | 45 | 24 | 24 | 5 | 5 | 22 | 2 | 0 | 0 | 0 | 4 | 1 | 0 | 3.83 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 7 | 7 | 3 | 4 | 4.47 | .329 | 1.45 | 9.4 | 3.8 | 4.9 | 48.1 | 50 | 24 | 24 | 7 | 20 | 26 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 5.13 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 7 | 7 | 3 | 2 | 4.71 | .304 | 1.27 | 8.8 | 2.8 | 5.7 | 49.2 | 48 | 26 | 26 | 5 | 15 | 31 | 3 | 0 | 0 | 0 | 3 | 2 | 2 | 4.10 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 7 | 7 | 5 | 1 | 3.35 | .301 | 1.27 | 9.5 | 1.9 | 5.6 | 51.0 | 54 | 20 | 19 | 6 | 11 | 32 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 3.98 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 18 | 0 | 1 | 2 | 3.80 | .340 | 1.55 | 10.3 | 3.9 | 8.6 | 21.1 | 24 | 9 | 9 | 4 | 9 | 20 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 4.86 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 14 | 0 | 2 | 1 | 5.06 | .294 | 1.25 | 9.6 | 1.7 | 12.4 | 16.0 | 17 | 9 | 9 | 2 | 3 | 22 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 2.44 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 9 | 0 | 0 | 0 | 3.38 | .256 | 1.03 | 6.3 | 3.6 | 6.3 | 10.2 | 7 | 7 | 4 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.10 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 6 | 0 | 0 | 0 | 7.11 | .296 | 1.26 | 6.0 | 6.0 | 13.5 | 6.1 | 4 | 5 | 5 | 0 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.00 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 4 | 0 | 0 | 0 | 5.06 | .385 | 1.88 | 16.2 | 1.8 | 3.6 | 5.1 | 9 | 3 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.80 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 30 | 2 | 0 | 0 | 0 | 8.44 | .448 | 2.44 | 16.2 | 7.2 | 0.0 | 5.1 | 9 | 5 | 5 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.00 |