| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 16 | 16 | 3 | 9 | 4.15 | .322 | 1.41 | 9.7 | 3.1 | 9.2 | 110.2 | 118 | 56 | 51 | 10 | 38 | 112 | 1 | 0 | 0 | 0 | 9 | 2 | 0 | 3.24 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 16 | 16 | 7 | 2 | 3.30 | .261 | 1.04 | 7.5 | 1.9 | 4.5 | 101.0 | 84 | 39 | 37 | 10 | 21 | 50 | 0 | 0 | 0 | 0 | 11 | 2 | 1 | 3.98 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 15 | 15 | 5 | 6 | 4.36 | .324 | 1.42 | 9.2 | 3.6 | 5.7 | 109.1 | 111 | 57 | 53 | 13 | 44 | 69 | 1 | 0 | 0 | 0 | 8 | 2 | 3 | 4.55 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 15 | 15 | 5 | 9 | 6.44 | .326 | 1.40 | 10.9 | 1.8 | 4.1 | 102.0 | 123 | 78 | 73 | 19 | 20 | 47 | 3 | 0 | 0 | 1 | 4 | 5 | 2 | 5.24 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 43 | 0 | 4 | 3 | 4.14 | .282 | 1.16 | 8.5 | 2.0 | 8.1 | 50.0 | 47 | 25 | 23 | 9 | 11 | 45 | 0 | 2 | 5 | 0 | 0 | 1 | 1 | 4.26 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 35 | 0 | 0 | 0 | 2.64 | .257 | 1.04 | 6.8 | 2.7 | 8.0 | 44.1 | 33 | 13 | 13 | 5 | 13 | 39 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.59 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 26 | 0 | 1 | 2 | 7.07 | .333 | 1.43 | 5.5 | 7.4 | 9.3 | 28.0 | 17 | 22 | 22 | 6 | 23 | 29 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 6.39 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 23 | 0 | 4 | 2 | 4.76 | .320 | 1.41 | 7.0 | 6.1 | 7.8 | 22.2 | 17 | 12 | 12 | 3 | 15 | 19 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 5.09 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 14 | 0 | 0 | 0 | 6.59 | .379 | 1.76 | 11.1 | 5.5 | 11.1 | 13.2 | 16 | 10 | 10 | 4 | 8 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 6.62 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 2 | 0 | 1 | 0 | 9.00 | .400 | 2.00 | 15.0 | 3.0 | 6.0 | 3.0 | 5 | 3 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.67 |