| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 13 | 15 | 4.03 | .314 | 1.34 | 8.7 | 3.4 | 9.1 | 238.2 | 231 | 113 | 107 | 28 | 90 | 241 | 1 | 0 | 0 | 1 | 19 | 7 | 3 | 3.73 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 33 | 33 | 12 | 16 | 4.65 | .304 | 1.28 | 9.2 | 2.3 | 5.9 | 244.0 | 250 | 143 | 126 | 29 | 63 | 160 | 9 | 0 | 0 | 0 | 16 | 6 | 6 | 4.08 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 32 | 32 | 12 | 13 | 4.51 | .303 | 1.30 | 8.5 | 3.3 | 4.8 | 219.2 | 206 | 117 | 110 | 36 | 80 | 118 | 2 | 0 | 0 | 0 | 16 | 1 | 2 | 5.17 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 13 | 12 | 4.67 | .315 | 1.36 | 9.3 | 3.0 | 6.0 | 215.2 | 221 | 118 | 112 | 26 | 72 | 143 | 4 | 0 | 0 | 1 | 15 | 4 | 3 | 4.30 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 91 | 0 | 9 | 5 | 2.82 | .275 | 1.12 | 7.4 | 2.7 | 9.2 | 115.0 | 94 | 38 | 36 | 14 | 35 | 117 | 0 | 7 | 5 | 0 | 0 | 2 | 1 | 3.51 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 49 | 0 | 4 | 4 | 4.94 | .355 | 1.65 | 9.6 | 5.4 | 10.5 | 47.1 | 50 | 30 | 26 | 10 | 28 | 55 | 0 | 3 | 4 | 0 | 0 | 0 | 2 | 5.21 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 36 | 0 | 2 | 2 | 2.97 | .259 | 1.05 | 5.3 | 4.3 | 9.3 | 36.1 | 21 | 12 | 12 | 3 | 17 | 37 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.44 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 9 | 0 | 1 | 0 | 3.77 | .328 | 1.40 | 9.0 | 3.9 | 8.4 | 14.1 | 14 | 6 | 6 | 1 | 6 | 13 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.57 |