| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 17 | 17 | 7 | 7 | 6.52 | .355 | 1.63 | 10.3 | 4.4 | 7.7 | 88.1 | 101 | 64 | 64 | 18 | 43 | 75 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 5.49 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 16 | 16 | 5 | 6 | 4.19 | .317 | 1.40 | 8.9 | 3.7 | 6.2 | 109.2 | 108 | 57 | 51 | 9 | 45 | 75 | 4 | 0 | 0 | 2 | 7 | 0 | 0 | 3.94 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 41 | 0 | 4 | 3 | 3.96 | .303 | 1.29 | 7.7 | 4.0 | 6.6 | 75.0 | 64 | 33 | 33 | 7 | 33 | 55 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.11 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 45 | 0 | 1 | 1 | 3.38 | .296 | 1.26 | 9.2 | 2.3 | 7.8 | 58.2 | 59 | 23 | 22 | 5 | 15 | 50 | 0 | 10 | 2 | 0 | 0 | 0 | 0 | 3.17 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 29 | 0 | 3 | 1 | 4.08 | .312 | 1.33 | 7.2 | 4.9 | 10.3 | 35.1 | 28 | 16 | 16 | 6 | 19 | 40 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 4.66 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 24 | 0 | 0 | 0 | 2.70 | .280 | 1.13 | 7.5 | 2.7 | 7.2 | 30.0 | 25 | 9 | 9 | 5 | 9 | 24 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.57 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 55 | 18 | 0 | 4 | 2 | 7.18 | .423 | 2.20 | 15.2 | 4.8 | 6.6 | 26.1 | 44 | 21 | 21 | 4 | 14 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.15 |