| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 19 | 19 | 10 | 7 | 3.10 | .268 | 1.07 | 7.4 | 2.3 | 9.8 | 127.2 | 104 | 44 | 44 | 13 | 32 | 138 | 0 | 0 | 0 | 0 | 15 | 4 | 0 | 3.01 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 85 | 18 | 18 | 4 | 5 | 5.54 | .305 | 1.32 | 9.5 | 2.4 | 5.9 | 91.0 | 96 | 62 | 56 | 21 | 24 | 60 | 0 | 0 | 0 | 0 | 5 | 0 | 2 | 5.47 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 18 | 17 | 7 | 7 | 3.44 | .277 | 1.13 | 7.2 | 3.0 | 6.5 | 120.1 | 96 | 52 | 46 | 12 | 40 | 87 | 2 | 0 | 0 | 0 | 11 | 2 | 1 | 3.90 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 16 | 16 | 6 | 6 | 4.43 | .312 | 1.34 | 9.4 | 2.7 | 5.7 | 109.2 | 114 | 65 | 54 | 14 | 33 | 69 | 6 | 0 | 0 | 0 | 7 | 2 | 1 | 4.37 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 48 | 0 | 2 | 2 | 2.12 | .251 | 0.97 | 4.4 | 4.4 | 11.1 | 63.2 | 31 | 16 | 15 | 3 | 31 | 78 | 0 | 3 | 2 | 0 | 0 | 2 | 4 | 2.71 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 32 | 0 | 2 | 4 | 3.25 | .265 | 1.03 | 5.8 | 3.5 | 7.0 | 36.0 | 23 | 13 | 13 | 4 | 14 | 28 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 4.22 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 22 | 0 | 2 | 2 | 4.38 | .308 | 1.30 | 6.8 | 5.3 | 11.3 | 24.2 | 18 | 12 | 12 | 3 | 14 | 30 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.00 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 15 | 0 | 1 | 0 | 3.00 | .267 | 1.10 | 4.7 | 5.1 | 4.7 | 21.0 | 11 | 8 | 7 | 1 | 12 | 11 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.29 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 11 | 0 | 0 | 0 | 2.77 | .188 | 0.69 | 3.5 | 2.8 | 11.8 | 13.0 | 5 | 4 | 4 | 2 | 4 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 9 | 0 | 0 | 0 | 1.64 | .327 | 1.45 | 6.5 | 6.5 | 6.5 | 11.0 | 8 | 2 | 2 | 1 | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.91 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 1 | 1 | 0 | 1 | 13.50 | .474 | 2.70 | 21.0 | 6.0 | 6.0 | 3.1 | 7 | 5 | 5 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |