| SP | Koufax, S.Koufax, Sandy >> | 33 | 1963 | L | 98 | 13 | 13 | 5 | 5 | 3.53 | .283 | 1.18 | 7.5 | 3.1 | 6.1 | 97.0 | 81 | 46 | 38 | 8 | 33 | 66 | 6 | 0 | 0 | 1 | 8 | 1 | 0 | 3.76 |
| SP | Colon, B.Colon, Bartolo >> | 31 | 1999 | R | 58 | 13 | 13 | 2 | 4 | 6.88 | .379 | 1.82 | 12.1 | 4.3 | 4.4 | 69.1 | 93 | 59 | 53 | 7 | 33 | 34 | 1 | 0 | 0 | 1 | 3 | 1 | 2 | 4.81 |
| SP | Anderson, B.Anderson, Brian >> | 31 | 1998 | L | 43 | 12 | 12 | 3 | 5 | 5.47 | .340 | 1.48 | 11.4 | 1.9 | 3.9 | 79.0 | 100 | 53 | 48 | 14 | 17 | 34 | 2 | 0 | 0 | 0 | 3 | 5 | 1 | 5.28 |
| RP | Munoz, A.Munoz, Andres >> | 28 | 2024 | R | 100 | 40 | 0 | 5 | 4 | 4.21 | .347 | 1.57 | 9.0 | 5.3 | 9.5 | 36.1 | 36 | 19 | 17 | 3 | 21 | 38 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 3.81 |
| RP | Franco, J.Franco, John >> | 30 | 1988 | L | 90 | 36 | 0 | 1 | 1 | 3.94 | .294 | 1.25 | 6.8 | 4.7 | 6.5 | 29.2 | 22 | 13 | 13 | 1 | 15 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.55 |
| RP | Vasquez, E.Vasquez, Esmerling >> | 27 | 2010 | R | 37 | 19 | 0 | 1 | 1 | 2.37 | .269 | 1.11 | 4.7 | 5.2 | 7.1 | 19.0 | 10 | 6 | 5 | 1 | 11 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.84 |
| RP | Branch, N.Branch, Norm >> | 30 | 1941 | R | 76 | 6 | 0 | 2 | 1 | 4.50 | .351 | 1.63 | 10.1 | 4.5 | 5.6 | 8.0 | 9 | 4 | 4 | 2 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.50 |
| RP | Rogers, K.Rogers, Kenny >> | 27 | 1989 | L | 71 | 22 | 0 | 2 | 1 | 2.59 | .223 | 0.86 | 6.8 | 1.1 | 5.6 | 24.1 | 18 | 9 | 7 | 3 | 3 | 15 | 0 | 3 | 1 | 0 | 0 | 0 | 3 | 3.75 |
| SP | Sanchez, A.Sanchez, Anibal >> | 28 | 2011 | R | 40 | 12 | 0 | 3 | 1 | 3.48 | .298 | 1.23 | 8.4 | 2.7 | 8.4 | 44.0 | 41 | 21 | 17 | 4 | 13 | 41 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.34 |