| SP | Schilling, C.Schilling, Curt + >> | 38 | 2004 | R | 86 | 32 | 32 | 11 | 13 | 3.91 | .287 | 1.21 | 8.8 | 2.1 | 5.9 | 225.2 | 219 | 108 | 98 | 16 | 53 | 147 | 5 | 0 | 0 | 3 | 16 | 1 | 7 | 3.34 |
| SP | Martinez, P.Martinez, Pedro + >> | 33 | 2004 | R | 73 | 32 | 32 | 10 | 11 | 4.42 | .320 | 1.39 | 9.5 | 3.1 | 8.3 | 197.1 | 207 | 101 | 97 | 19 | 68 | 181 | 1 | 0 | 0 | 0 | 18 | 4 | 4 | 3.51 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 67 | 31 | 31 | 12 | 11 | 4.25 | .310 | 1.31 | 8.9 | 3.0 | 5.4 | 201.1 | 198 | 104 | 95 | 19 | 66 | 121 | 1 | 0 | 0 | 0 | 21 | 7 | 0 | 4.11 |
| SP | Arroyo, B.Arroyo, Bronson + >> | 27 | 2004 | R | 58 | 30 | 30 | 8 | 13 | 4.26 | .325 | 1.44 | 9.1 | 3.9 | 4.9 | 173.1 | 174 | 92 | 82 | 16 | 75 | 95 | 0 | 0 | 0 | 0 | 13 | 1 | 4 | 4.42 |
| SP | Wakefield, T.Wakefield, Tim + >> | 38 | 2004 | R | 31 | 29 | 29 | 4 | 10 | 5.29 | .351 | 1.57 | 9.3 | 4.8 | 4.3 | 136.0 | 140 | 87 | 80 | 12 | 73 | 65 | 0 | 0 | 0 | 0 | 3 | 8 | 8 | 4.98 |
| CL | Foulke, K.Foulke, Keith + >> | 32 | 2004 | R | 93 | 56 | 0 | 1 | 5 | 3.67 | .258 | 1.04 | 6.9 | 2.5 | 6.0 | 61.1 | 47 | 25 | 25 | 3 | 17 | 41 | 0 | 25 | 4 | 0 | 0 | 0 | 0 | 3.13 |
| RP | Mendoza, R.Mendoza, Ramiro + >> | 32 | 2004 | R | 83 | 84 | 0 | 13 | 4 | 3.74 | .261 | 1.05 | 7.6 | 1.9 | 4.3 | 113.0 | 95 | 49 | 47 | 7 | 24 | 54 | 0 | 1 | 4 | 0 | 0 | 1 | 3 | 3.51 |
| RP | Embree, A.Embree, Alan + >> | 34 | 2004 | L | 68 | 77 | 0 | 0 | 6 | 3.64 | .308 | 1.33 | 8.8 | 3.2 | 3.8 | 99.0 | 97 | 41 | 40 | 9 | 35 | 42 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 4.39 |
| RP | Timlin, M.Timlin, Mike + >> | 38 | 2004 | R | 57 | 67 | 0 | 4 | 2 | 5.61 | .363 | 1.69 | 11.8 | 3.5 | 5.0 | 67.1 | 88 | 46 | 42 | 10 | 26 | 37 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 5.04 |
| RP | Myers, M.Myers, Mike + >> | 35 | 2004 | L | 20 | 56 | 0 | 4 | 2 | 5.07 | .325 | 1.43 | 8.6 | 4.4 | 5.6 | 60.1 | 57 | 35 | 34 | 5 | 29 | 37 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 4.35 |