| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 8 | 8 | 3 | 3 | 3.86 | .260 | 1.02 | 6.6 | 2.6 | 6.1 | 56.0 | 41 | 27 | 24 | 8 | 16 | 38 | 2 | 0 | 0 | 0 | 5 | 2 | 0 | 4.46 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 69 | 8 | 8 | 1 | 5 | 6.34 | .356 | 1.64 | 10.8 | 3.9 | 7.0 | 44.0 | 53 | 34 | 31 | 11 | 19 | 34 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 6.07 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 55 | 7 | 7 | 3 | 3 | 4.74 | .325 | 1.42 | 9.2 | 3.8 | 6.5 | 43.2 | 44 | 23 | 23 | 5 | 18 | 31 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.40 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 54 | 7 | 7 | 2 | 4 | 8.23 | .367 | 1.71 | 9.5 | 5.9 | 8.2 | 35.0 | 37 | 33 | 32 | 7 | 23 | 32 | 0 | 0 | 0 | 0 | 1 | 1 | 3 | 5.83 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 94 | 21 | 0 | 2 | 2 | 5.33 | .356 | 1.50 | 7.6 | 6.1 | 7.2 | 25.1 | 21 | 15 | 15 | 2 | 17 | 20 | 0 | 2 | 1 | 0 | 0 | 4 | 4 | 4.96 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 17 | 0 | 0 | 1 | 1.83 | .253 | 1.02 | 6.2 | 3.3 | 9.0 | 19.2 | 13 | 6 | 4 | 2 | 7 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.47 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 57 | 14 | 0 | 0 | 0 | 1.37 | .169 | 0.56 | 3.8 | 1.4 | 9.5 | 19.2 | 8 | 4 | 3 | 1 | 3 | 20 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.21 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 48 | 14 | 0 | 2 | 0 | 5.17 | .347 | 1.60 | 8.4 | 6.6 | 10.8 | 15.2 | 14 | 9 | 9 | 2 | 11 | 18 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.53 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 40 | 10 | 0 | 1 | 0 | 3.60 | .348 | 1.50 | 5.4 | 8.1 | 11.7 | 10.0 | 6 | 4 | 4 | 1 | 9 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.70 |
| SP | Norris, M.Norris, Mike >> | 25 | 1980 | R | 45 | 6 | 0 | 1 | 0 | 6.10 | .367 | 1.74 | 11.7 | 4.5 | 5.4 | 10.1 | 13 | 7 | 7 | 5 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.80 |