| SP | Martinez, P.Martinez, Pedro † $$ >> | 29 | 2000 | R | 100 | 33 | 33 | 13 | 12 | 3.12 | .274 | 1.11 | 7.1 | 2.9 | 9.1 | 225.0 | 178 | 79 | 78 | 28 | 72 | 227 | 0 | 0 | 0 | 0 | 24 | 5 | 4 | 3.63 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 33 | 33 | 8 | 6 | 4.65 | .320 | 1.39 | 9.2 | 3.3 | 9.8 | 186.0 | 190 | 99 | 96 | 34 | 69 | 202 | 1 | 0 | 0 | 1 | 17 | 4 | 2 | 4.38 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 32 | 32 | 6 | 18 | 5.37 | .321 | 1.39 | 9.1 | 3.5 | 8.6 | 169.1 | 171 | 103 | 101 | 29 | 65 | 161 | 0 | 0 | 0 | 0 | 10 | 4 | 7 | 4.55 |
| SP | Strider, S.Strider, Spencer # >> | 23 | 2022 | R | 80 | 31 | 31 | 6 | 11 | 4.39 | .320 | 1.37 | 8.6 | 3.7 | 10.4 | 135.1 | 129 | 66 | 66 | 20 | 56 | 156 | 0 | 0 | 0 | 0 | 3 | 6 | 5 | 3.99 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 67 | 32 | 31 | 12 | 8 | 3.63 | .310 | 1.32 | 7.6 | 4.3 | 9.0 | 183.2 | 155 | 75 | 74 | 17 | 87 | 184 | 0 | 0 | 0 | 0 | 19 | 5 | 2 | 3.70 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 78 | 0 | 9 | 5 | 4.48 | .289 | 1.19 | 7.8 | 3.0 | 8.7 | 94.1 | 81 | 47 | 47 | 18 | 31 | 91 | 0 | 2 | 1 | 0 | 0 | 3 | 6 | 4.64 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 73 | 56 | 0 | 1 | 2 | 4.95 | .323 | 1.38 | 9.1 | 3.4 | 11.7 | 63.2 | 64 | 36 | 35 | 18 | 24 | 82 | 0 | 0 | 1 | 0 | 0 | 3 | 4 | 5.40 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 42 | 0 | 3 | 1 | 3.35 | .278 | 1.14 | 8.3 | 1.9 | 9.0 | 51.0 | 47 | 19 | 19 | 11 | 11 | 51 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.51 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 64 | 31 | 0 | 3 | 0 | 3.40 | .296 | 1.26 | 8.1 | 3.5 | 10.8 | 39.2 | 35 | 15 | 15 | 7 | 15 | 47 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.08 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 57 | 0 | 3 | 12 | 4.95 | .307 | 1.28 | 8.7 | 2.9 | 8.5 | 56.1 | 54 | 33 | 31 | 11 | 18 | 53 | 0 | 24 | 3 | 0 | 0 | 3 | 3 | 4.79 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 4 | 1 | 1 | 1 | 4.09 | .340 | 1.55 | 11.5 | 2.5 | 8.2 | 11.0 | 14 | 5 | 5 | 1 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.18 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 86 | 67 | 0 | 2 | 2 | 3.46 | .278 | 1.14 | 6.6 | 3.7 | 10.4 | 78.0 | 57 | 30 | 30 | 9 | 32 | 90 | 0 | 6 | 4 | 0 | 0 | 1 | 5 | 3.46 |