| SP | Santana, J.Santana, Johan $ >> | 25 | 2004 | L | 91 | 14 | 14 | 8 | 4 | 4.85 | .319 | 1.37 | 9.2 | 3.2 | 8.6 | 91.0 | 93 | 55 | 49 | 17 | 32 | 87 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 4.67 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 13 | 13 | 2 | 9 | 6.61 | .323 | 1.42 | 9.5 | 3.4 | 4.6 | 77.2 | 81 | 57 | 57 | 23 | 29 | 39 | 3 | 0 | 0 | 0 | 3 | 1 | 1 | 7.04 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 70 | 13 | 13 | 5 | 4 | 4.54 | .316 | 1.31 | 8.9 | 3.0 | 7.2 | 85.1 | 84 | 45 | 43 | 17 | 28 | 68 | 0 | 0 | 0 | 0 | 7 | 6 | 0 | 5.20 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 32 | 0 | 0 | 7 | 5.40 | .274 | 1.07 | 8.1 | 1.5 | 12.0 | 30.0 | 27 | 18 | 18 | 6 | 5 | 40 | 0 | 16 | 3 | 0 | 0 | 2 | 1 | 3.63 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 33 | 0 | 3 | 2 | 3.82 | .232 | 0.88 | 5.4 | 2.6 | 8.5 | 35.1 | 21 | 16 | 15 | 7 | 10 | 33 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.66 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 26 | 0 | 3 | 0 | 2.17 | .304 | 1.31 | 7.1 | 4.7 | 10.6 | 29.0 | 23 | 9 | 7 | 5 | 15 | 34 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.45 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 72 | 21 | 0 | 1 | 1 | 2.89 | .273 | 1.07 | 7.5 | 2.5 | 10.5 | 18.2 | 15 | 6 | 6 | 3 | 5 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.83 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 68 | 16 | 0 | 1 | 0 | 1.50 | .273 | 1.13 | 6.0 | 4.1 | 8.6 | 24.0 | 16 | 4 | 4 | 2 | 11 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.54 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 64 | 10 | 0 | 2 | 0 | 3.09 | .276 | 1.12 | 6.7 | 3.6 | 9.4 | 43.2 | 32 | 16 | 15 | 6 | 17 | 45 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.98 |