| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 85 | 37 | 37 | 12 | 14 | 4.67 | .316 | 1.38 | 8.9 | 3.5 | 9.1 | 212.0 | 210 | 113 | 110 | 30 | 82 | 214 | 1 | 0 | 0 | 1 | 19 | 2 | 2 | 4.01 |
| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 97 | 35 | 35 | 18 | 10 | 3.60 | .284 | 1.18 | 7.0 | 3.6 | 9.5 | 240.0 | 186 | 99 | 96 | 29 | 96 | 254 | 1 | 0 | 0 | 1 | 24 | 4 | 6 | 3.70 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 71 | 33 | 33 | 4 | 12 | 5.74 | .341 | 1.53 | 9.5 | 4.3 | 7.6 | 152.0 | 160 | 104 | 97 | 32 | 73 | 128 | 0 | 0 | 0 | 0 | 7 | 3 | 9 | 5.55 |
| SP | Messersmith, A.Messersmith, Andy # >> | 30 | 1975 | R | 42 | 33 | 33 | 13 | 12 | 5.63 | .335 | 1.46 | 9.2 | 4.0 | 6.8 | 179.0 | 182 | 121 | 112 | 32 | 80 | 135 | 1 | 0 | 0 | 0 | 13 | 8 | 5 | 5.29 |
| RP | Gossage, R.Gossage, Rich # $$ >> | 30 | 1981 | R | 87 | 88 | 0 | 13 | 6 | 4.60 | .329 | 1.42 | 8.5 | 4.3 | 9.3 | 133.0 | 125 | 68 | 68 | 17 | 64 | 138 | 0 | 2 | 3 | 0 | 0 | 7 | 3 | 4.19 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 87 | 0 | 5 | 2 | 4.33 | .320 | 1.40 | 7.8 | 4.9 | 9.6 | 97.2 | 84 | 49 | 47 | 18 | 53 | 104 | 0 | 0 | 4 | 0 | 0 | 1 | 7 | 4.94 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 34 | 70 | 0 | 9 | 0 | 2.76 | .274 | 1.12 | 6.4 | 3.8 | 8.1 | 84.2 | 60 | 28 | 26 | 12 | 35 | 76 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.33 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 80 | 0 | 4 | 7 | 4.40 | .295 | 1.26 | 9.1 | 2.2 | 8.8 | 90.0 | 91 | 44 | 44 | 11 | 22 | 88 | 0 | 3 | 8 | 0 | 0 | 0 | 0 | 3.37 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 96 | 81 | 0 | 0 | 3 | 2.06 | .258 | 1.02 | 6.9 | 2.3 | 9.1 | 87.1 | 67 | 20 | 20 | 6 | 22 | 88 | 0 | 47 | 4 | 0 | 0 | 2 | 1 | 2.70 |