| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 8 | 8 | 4 | 1 | 2.56 | .279 | 1.16 | 7.4 | 3.1 | 8.7 | 52.2 | 43 | 15 | 15 | 6 | 18 | 50 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 3.62 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 8 | 8 | 7 | 1 | 2.51 | .236 | 0.89 | 5.2 | 2.8 | 9.6 | 57.1 | 33 | 17 | 16 | 5 | 18 | 61 | 1 | 0 | 0 | 1 | 6 | 2 | 1 | 3.05 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 70 | 7 | 7 | 0 | 3 | 6.28 | .381 | 1.81 | 10.6 | 6.1 | 7.1 | 28.2 | 33 | 25 | 20 | 5 | 19 | 22 | 0 | 0 | 0 | 0 | 1 | 1 | 3 | 5.89 |
| SP | Messersmith, A.Messersmith, Andy # >> | 30 | 1975 | R | 39 | 7 | 7 | 2 | 2 | 5.98 | .322 | 1.38 | 9.2 | 3.4 | 6.5 | 40.2 | 41 | 27 | 27 | 8 | 15 | 29 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 5.43 |
| RP | Gossage, R.Gossage, Rich $$ >> | 30 | 1981 | R | 87 | 20 | 0 | 3 | 2 | 4.06 | .316 | 1.39 | 8.4 | 4.1 | 8.1 | 31.0 | 29 | 14 | 14 | 3 | 14 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.81 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 19 | 0 | 1 | 0 | 3.00 | .259 | 1.05 | 6.0 | 3.4 | 9.4 | 21.0 | 14 | 7 | 7 | 3 | 8 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.90 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 33 | 12 | 0 | 4 | 0 | 6.59 | .328 | 1.39 | 7.6 | 5.5 | 9.0 | 13.2 | 11 | 10 | 10 | 3 | 8 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.08 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 83 | 18 | 0 | 0 | 1 | 5.49 | .298 | 1.27 | 10.9 | 0.9 | 7.6 | 19.2 | 23 | 12 | 12 | 3 | 2 | 16 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.68 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 20 | 0 | 0 | 1 | 2.11 | .289 | 1.22 | 8.6 | 2.6 | 10.7 | 21.1 | 20 | 5 | 5 | 1 | 6 | 25 | 0 | 12 | 2 | 0 | 0 | 0 | 0 | 2.10 |