| SP | Gibson, B.Gibson, Bob $$ >> | 33 | 1968 | R | 93 | 10 | 10 | 6 | 0 | 3.45 | .295 | 1.18 | 7.6 | 3.1 | 6.6 | 75.2 | 63 | 30 | 29 | 7 | 26 | 55 | 4 | 0 | 0 | 1 | 7 | 6 | 2 | 4.03 |
| SP | Reulbach, E.Reulbach, Ed $ >> | 24 | 1906 | R | 60 | 10 | 10 | 2 | 6 | 4.34 | .337 | 1.51 | 9.1 | 4.5 | 4.4 | 66.1 | 67 | 34 | 32 | 8 | 33 | 32 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 5.15 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 10 | 10 | 3 | 6 | 5.12 | .313 | 1.37 | 9.4 | 2.9 | 8.6 | 65.0 | 68 | 38 | 37 | 9 | 21 | 62 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 3.86 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 9 | 9 | 4 | 2 | 6.31 | .345 | 1.56 | 10.2 | 3.9 | 7.4 | 51.1 | 58 | 36 | 36 | 13 | 22 | 42 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 6.02 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 10 | 10 | 4 | 3 | 4.33 | .285 | 1.19 | 8.7 | 2.1 | 7.5 | 68.2 | 66 | 35 | 33 | 15 | 16 | 57 | 1 | 0 | 0 | 1 | 5 | 0 | 2 | 4.90 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 25 | 0 | 2 | 2 | 2.18 | .244 | 0.94 | 4.6 | 3.8 | 8.7 | 33.0 | 17 | 8 | 8 | 3 | 14 | 32 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.61 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 18 | 0 | 1 | 1 | 5.30 | .356 | 1.61 | 10.0 | 5.0 | 14.0 | 18.2 | 20 | 11 | 11 | 3 | 10 | 28 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.89 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 10 | 0 | 0 | 1 | 4.63 | .340 | 1.54 | 11.5 | 3.3 | 11.5 | 11.2 | 14 | 8 | 6 | 2 | 4 | 14 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 10 | 0 | 2 | 1 | 0.84 | .289 | 1.22 | 2.7 | 9.0 | 9.9 | 10.2 | 3 | 1 | 1 | 0 | 10 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.80 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 7 | 0 | 0 | 0 | 2.84 | .321 | 1.26 | 9.0 | 3.0 | 9.0 | 6.1 | 6 | 2 | 2 | 0 | 2 | 6 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 2.50 |