| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 34 | 34 | 18 | 11 | 3.40 | .274 | 1.12 | 7.2 | 2.9 | 8.9 | 227.2 | 181 | 91 | 86 | 32 | 73 | 225 | 0 | 0 | 0 | 0 | 23 | 4 | 0 | 3.87 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 32 | 32 | 8 | 13 | 5.06 | .313 | 1.32 | 8.7 | 3.3 | 5.2 | 220.2 | 212 | 135 | 124 | 28 | 80 | 128 | 2 | 0 | 0 | 1 | 16 | 10 | 4 | 4.72 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 32 | 32 | 9 | 15 | 4.89 | .324 | 1.43 | 9.3 | 3.6 | 7.7 | 217.1 | 225 | 121 | 118 | 30 | 86 | 186 | 2 | 0 | 0 | 1 | 16 | 1 | 6 | 4.29 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 12 | 13 | 4.18 | .320 | 1.38 | 8.5 | 3.9 | 5.5 | 219.2 | 208 | 109 | 102 | 20 | 95 | 135 | 6 | 0 | 0 | 3 | 17 | 7 | 1 | 4.35 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 91 | 0 | 3 | 6 | 4.83 | .317 | 1.39 | 8.2 | 4.4 | 9.5 | 119.1 | 108 | 65 | 64 | 18 | 58 | 126 | 0 | 6 | 5 | 0 | 0 | 0 | 0 | 4.31 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 75 | 0 | 4 | 4 | 4.85 | .345 | 1.56 | 8.3 | 5.8 | 9.9 | 81.2 | 75 | 46 | 44 | 10 | 52 | 89 | 0 | 9 | 4 | 0 | 0 | 2 | 5 | 4.41 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 62 | 0 | 5 | 2 | 4.87 | .338 | 1.53 | 8.7 | 5.2 | 9.7 | 64.2 | 62 | 35 | 35 | 8 | 37 | 69 | 0 | 5 | 2 | 0 | 0 | 0 | 2 | 4.20 |
| RP | Myers, R.Myers, Randy # >> | 26 | 1988 | L | 59 | 49 | 0 | 3 | 4 | 4.42 | .307 | 1.31 | 9.8 | 2.0 | 8.0 | 55.0 | 60 | 28 | 27 | 6 | 12 | 49 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 3.35 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 53 | 1 | 0 | 0 | 0 | 13.50 | .333 | 1.50 | - | - | - | 0.2 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 60 | 26 | 0 | 4 | 1 | 5.29 | .350 | 1.62 | 10.1 | 4.5 | 6.6 | 34.0 | 38 | 20 | 20 | 3 | 17 | 25 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.18 |