| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 26 | 26 | 8 | 11 | 3.84 | .269 | 1.09 | 7.9 | 2.0 | 7.9 | 175.2 | 153 | 77 | 75 | 21 | 38 | 154 | 4 | 0 | 0 | 0 | 15 | 3 | 2 | 3.50 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 26 | 26 | 7 | 14 | 5.10 | .303 | 1.28 | 8.7 | 2.9 | 9.0 | 160.2 | 155 | 93 | 91 | 31 | 51 | 160 | 1 | 0 | 0 | 0 | 13 | 4 | 3 | 4.55 |
| SP | Joss, A.Joss, Addie # $$ >> | 28 | 1908 | R | 83 | 25 | 25 | 8 | 11 | 4.46 | .309 | 1.32 | 10.2 | 1.7 | 4.3 | 171.2 | 194 | 92 | 85 | 15 | 32 | 81 | 3 | 0 | 0 | 0 | 14 | 4 | 1 | 3.82 |
| SP | Clemens, R.Clemens, Roger † >> | 35 | 1997 | R | 35 | 23 | 23 | 14 | 6 | 3.43 | .292 | 1.20 | 7.3 | 3.5 | 8.3 | 168.0 | 136 | 66 | 64 | 12 | 66 | 155 | 3 | 0 | 0 | 2 | 13 | 6 | 0 | 3.37 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 53 | 0 | 5 | 5 | 3.40 | .246 | 0.96 | 5.4 | 3.2 | 11.4 | 53.0 | 32 | 20 | 20 | 4 | 19 | 67 | 0 | 35 | 6 | 0 | 0 | 1 | 5 | 2.58 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 47 | 0 | 0 | 4 | 5.17 | .329 | 1.46 | 8.7 | 4.6 | 5.6 | 55.2 | 53 | 32 | 32 | 10 | 28 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.71 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 38 | 0 | 5 | 1 | 4.57 | .291 | 1.21 | 9.4 | 1.5 | 7.5 | 41.1 | 43 | 21 | 21 | 10 | 7 | 34 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.10 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 23 | 0 | 1 | 2 | 4.95 | .388 | 1.90 | 8.6 | 8.6 | 10.8 | 20.0 | 19 | 11 | 11 | 3 | 19 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.40 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 24 | 0 | 1 | 0 | 4.13 | .294 | 1.25 | 8.3 | 3.0 | 5.6 | 24.0 | 22 | 11 | 11 | 5 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.46 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 19 | 10 | 3 | 3 | 6.59 | .326 | 1.45 | 9.2 | 4.0 | 4.7 | 95.2 | 97 | 71 | 70 | 17 | 42 | 50 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 5.60 |