| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 10 | 10 | 4 | 6 | 4.52 | .317 | 1.38 | 9.4 | 3.1 | 7.3 | 69.2 | 72 | 41 | 35 | 12 | 24 | 56 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 4.72 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 10 | 10 | 4 | 5 | 4.03 | .285 | 1.18 | 8.4 | 2.3 | 5.9 | 73.2 | 68 | 36 | 33 | 8 | 19 | 48 | 3 | 0 | 0 | 0 | 6 | 1 | 0 | 3.93 |
| SP | Brown, M.Brown, Mordecai $ >> | 32 | 1908 | R | 85 | 10 | 10 | 5 | 5 | 3.29 | .283 | 1.19 | 8.3 | 2.4 | 4.8 | 68.1 | 63 | 26 | 25 | 5 | 18 | 36 | 3 | 0 | 0 | 0 | 7 | 0 | 2 | 3.69 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 24 | 0 | 2 | 1 | 1.29 | .276 | 1.14 | 7.4 | 2.9 | 6.4 | 28.0 | 23 | 5 | 4 | 1 | 9 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 18 | 0 | 0 | 0 | 5.94 | .315 | 1.38 | 9.6 | 3.4 | 9.6 | 16.2 | 17 | 11 | 11 | 1 | 6 | 17 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 2.81 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 5 | 0 | 0 | 0 | 4.76 | .292 | 1.06 | 10.8 | 0.0 | 12.6 | 5.2 | 6 | 3 | 3 | 1 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.40 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 9 | 0 | 0 | 0 | 4.00 | .308 | 1.33 | 10.0 | 2.0 | 5.0 | 9.0 | 10 | 4 | 4 | 2 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.44 |