| SP | McCullers, L.McCullers, Lance >> | 23 | 2016 | R | 33 | 26 | 26 | 8 | 11 | 4.35 | .346 | 1.56 | 9.4 | 4.6 | 9.4 | 153.0 | 160 | 76 | 74 | 20 | 79 | 160 | 0 | 0 | 0 | 0 | 12 | 4 | 11 | 4.24 |
| SP | Sanchez, A.Sanchez, Aaron # >> | 23 | 2016 | R | 80 | 34 | 34 | 11 | 14 | 4.37 | .303 | 1.27 | 8.8 | 2.7 | 7.2 | 224.1 | 219 | 121 | 109 | 28 | 66 | 179 | 1 | 0 | 0 | 0 | 19 | 8 | 4 | 4.02 |
| SP | Arrieta, J.Arrieta, Jake >> | 30 | 2016 | R | 94 | 32 | 32 | 7 | 15 | 5.12 | .349 | 1.56 | 9.3 | 4.8 | 7.7 | 195.0 | 201 | 113 | 111 | 28 | 103 | 166 | 1 | 0 | 0 | 0 | 15 | 9 | 9 | 4.89 |
| SP | Colon, B.Colon, Bartolo >> | 43 | 2016 | R | 49 | 26 | 23 | 8 | 12 | 5.10 | .343 | 1.50 | 11.7 | 1.8 | 6.6 | 139.1 | 181 | 87 | 79 | 16 | 28 | 102 | 0 | 0 | 0 | 0 | 10 | 9 | 0 | 3.83 |
| SP | Porcello, R.Porcello, Rick >> | 27 | 2016 | R | 88 | 28 | 20 | 7 | 12 | 4.27 | .312 | 1.33 | 9.6 | 2.4 | 7.1 | 141.1 | 151 | 77 | 67 | 22 | 37 | 112 | 0 | 2 | 1 | 0 | 9 | 4 | 1 | 4.31 |
| SU | Buchter, R.Buchter, Ryan >> | 29 | 2016 | L | 91 | 79 | 0 | 4 | 1 | 2.74 | .285 | 1.16 | 5.7 | 4.8 | 10.1 | 92.0 | 58 | 31 | 28 | 7 | 49 | 103 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 3.45 |
| RP | Siegrist, K.Siegrist, Kevin >> | 26 | 2016 | L | 73 | 92 | 0 | 6 | 0 | 2.41 | .269 | 1.06 | 6.6 | 2.9 | 9.4 | 86.0 | 63 | 27 | 23 | 8 | 28 | 90 | 0 | 2 | 2 | 0 | 0 | 4 | 3 | 3.23 |
| CL | Feliz, N.Feliz, Neftali >> | 28 | 2016 | R | 67 | 67 | 0 | 4 | 5 | 2.92 | .266 | 1.04 | 6.0 | 3.4 | 8.7 | 71.0 | 47 | 26 | 23 | 6 | 27 | 69 | 0 | 28 | 3 | 0 | 0 | 3 | 2 | 3.42 |