| SP | Strasburg, S.Strasburg, Stephen # >> | 27 | 2016 | R | 93 | 16 | 16 | 6 | 6 | 3.93 | .290 | 1.19 | 8.6 | 2.1 | 10.8 | 94.0 | 90 | 41 | 41 | 14 | 22 | 113 | 1 | 0 | 0 | 1 | 10 | 3 | 1 | 3.33 |
| SP | Porcello, R.Porcello, Rick >> | 27 | 2016 | R | 88 | 16 | 16 | 5 | 4 | 5.00 | .334 | 1.46 | 11.3 | 1.9 | 7.5 | 99.0 | 124 | 58 | 55 | 16 | 21 | 82 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 4.20 |
| SP | Odorizzi, J.Odorizzi, Jake >> | 26 | 2016 | R | 76 | 15 | 15 | 8 | 4 | 4.73 | .337 | 1.49 | 9.7 | 3.7 | 8.0 | 78.0 | 84 | 43 | 41 | 12 | 32 | 69 | 0 | 0 | 0 | 0 | 6 | 3 | 0 | 4.58 |
| SP | Samardzija, J.Samardzija, Jeff >> | 31 | 2016 | R | 68 | 15 | 15 | 3 | 8 | 7.57 | .365 | 1.64 | 11.0 | 3.8 | 7.3 | 69.0 | 84 | 60 | 58 | 13 | 29 | 56 | 0 | 0 | 0 | 0 | 3 | 6 | 1 | 5.35 |
| SP | Hamels, C.Hamels, Cole >> | 33 | 2016 | L | 60 | 17 | 15 | 6 | 3 | 4.94 | .306 | 1.29 | 8.9 | 2.7 | 9.9 | 93.0 | 92 | 54 | 51 | 14 | 28 | 102 | 2 | 0 | 0 | 2 | 8 | 3 | 2 | 3.76 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 28 | 2016 | R | 88 | 34 | 0 | 5 | 2 | 3.18 | .320 | 1.31 | 7.6 | 4.4 | 11.3 | 39.2 | 33 | 14 | 14 | 3 | 19 | 49 | 0 | 12 | 4 | 0 | 0 | 4 | 6 | 3.26 |
| SU | Cishek, S.Cishek, Steve >> | 30 | 2016 | R | 85 | 46 | 0 | 3 | 6 | 8.06 | .360 | 1.67 | 9.0 | 6.0 | 10.9 | 48.0 | 48 | 46 | 43 | 8 | 32 | 58 | 0 | 0 | 4 | 0 | 0 | 1 | 2 | 4.81 |
| RP | Salas, F.Salas, Fernando >> | 31 | 2016 | R | 54 | 32 | 0 | 0 | 0 | 3.67 | .277 | 1.13 | 7.2 | 3.1 | 6.8 | 41.2 | 33 | 17 | 17 | 5 | 14 | 31 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.17 |