| SP | Verlander, J.Verlander, Justin >> | 33 | 2016 | R | 98 | 30 | 30 | 11 | 10 | 3.03 | .282 | 1.12 | 6.9 | 3.2 | 9.2 | 193.0 | 148 | 68 | 65 | 13 | 68 | 198 | 1 | 0 | 0 | 0 | 20 | 11 | 5 | 3.05 |
| SP | Fulmer, M.Fulmer, Michael † # >> | 23 | 2016 | R | 85 | 29 | 29 | 14 | 6 | 4.16 | .299 | 1.20 | 8.9 | 2.0 | 7.4 | 168.2 | 166 | 80 | 78 | 22 | 37 | 138 | 0 | 0 | 0 | 0 | 16 | 13 | 2 | 3.95 |
| SP | Eickhoff, J.Eickhoff, Jerad >> | 25 | 2016 | R | 72 | 29 | 29 | 12 | 11 | 4.41 | .333 | 1.42 | 10.2 | 2.6 | 7.3 | 169.1 | 192 | 93 | 83 | 23 | 48 | 138 | 0 | 0 | 0 | 0 | 15 | 14 | 9 | 4.24 |
| SP | DeSclafani, A.DeSclafani, Anthony # >> | 26 | 2016 | R | 63 | 30 | 29 | 8 | 9 | 5.04 | .352 | 1.59 | 11.1 | 3.3 | 7.1 | 153.2 | 188 | 89 | 86 | 26 | 56 | 121 | 0 | 0 | 0 | 0 | 10 | 6 | 4 | 4.84 |
| CL | Jones, N.Jones, Nate † >> | 30 | 2016 | R | 94 | 83 | 0 | 8 | 4 | 3.34 | .282 | 1.15 | 8.0 | 2.4 | 10.0 | 91.2 | 81 | 34 | 34 | 12 | 24 | 101 | 0 | 31 | 2 | 0 | 0 | 3 | 6 | 3.38 |
| SU | Osuna, R.Osuna, Roberto >> | 21 | 2016 | R | 86 | 91 | 0 | 5 | 6 | 4.27 | .331 | 1.43 | 9.8 | 3.1 | 10.7 | 99.0 | 108 | 48 | 47 | 9 | 34 | 118 | 0 | 2 | 9 | 0 | 0 | 5 | 4 | 2.98 |
| RP | Colome, A.Colome, Alex >> | 27 | 2016 | R | 77 | 95 | 0 | 6 | 3 | 3.02 | .279 | 1.12 | 8.1 | 2.0 | 10.8 | 110.1 | 99 | 38 | 37 | 12 | 25 | 132 | 0 | 2 | 6 | 0 | 0 | 4 | 3 | 2.81 |
| RP | Barraclough, K.Barraclough, Kyle >> | 26 | 2016 | R | 70 | 81 | 0 | 6 | 5 | 3.27 | .325 | 1.39 | 7.5 | 5.0 | 13.4 | 93.2 | 78 | 34 | 34 | 9 | 52 | 138 | 0 | 3 | 1 | 0 | 0 | 5 | 5 | 3.13 |